Evidence map›Paper›PMID 23995915›Full record

ReviewArchivum immunologiae et therapiae experimentalis2014

Plant polyisoprenoids and control of cholesterol level.

Alexander V Pronin, Leonid L Danilov, Alexander N Narovlyansky, Alexander V Sanin

Abstract readReview
In one paragraph

Review in Archivum immunologiae et therapiae experimentalis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. New Approaches to the Prevention and Treatment of Viral Diseases.Archivum immunologiae et therapiae experimentalis · 2021
    Review
  4. Effects ofAntioxidants (Basel, Switzerland) · 2021
    Article
  5. Article
  6. Anticancer Activity of Polyisoprenoids fromIranian journal of pharmaceutical research : IJPR · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander V ProninN. F. Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia, proninalexander@yandex.ru.
Leonid L Danilov
Alexander N Narovlyansky
Alexander V Sanin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of plant polyisoprenoids (polyprenols and polyprenyl phosphates) to diminish the levels of serum cholesterol affecting its biosynthetic pathway are highlighted here. Possible mechanism of such process is discussed. It is also noted that polyisoprenoids can prevent toxic injuries of the liver and restore disturbed hepatic functions. The possibility of polyprenyl phosphates to reveal at the same time anti-inflammatory action suppressing lipoxygenase activity and lowering the levels of proinflammatory cytokines will be illustrated. Attention will be focused on the potential usefulness of plant polyisoprenoids in the course of prevention and treatment of hypercholesterolemia. High efficiency for combined use of polyprenyl phosphate and β-sitosterol, which leads to substantial enhancement of the ability to overcome hypercholesterolemia versus the individual constituents will be demonstrated.

Indexed as

AnimalsAnti-Inflammatory AgentsAntineoplastic Combined Chemotherapy ProtocolsChemical and Drug Induced Liver InjuryCholesterolHumansHypercholesterolemiaLipoxygenasePhytotherapyPlantsSitosterolsTerpenesAnti-Inflammatory AgentsCholesterolgamma-sitosterolLipoxygenaseSitosterolsTerpenes

Identifiers

PMID23995915
PMCPMC3898360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.