ArticleEuropean journal of applied physiology2013
Changes in phosphocreatine concentration of skeletal muscle during high-intensity intermittent exercise in children and adults.
Article in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Building for the Future: A Systematic Review of the Effects of Eccentric Resistance Training on Measures of Physical Performance in Youth Athletes.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Differences in time to task failure and fatigability between children and young adults: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Neuromuscular fatigue differences between prepubertal boys and men after maximal concentric versus eccentric isokinetic knee extensions.European journal of applied physiology · 2026Trial
- Artificial mitochondria ameliorates osteoarthritis through restoring cellular energy metabolism homeostasis.Bioactive materials · 2026Article
- Physiological differences in cardiopulmonary exercise testing between children and adults.Pediatric research · 2026Article
- Neuromuscular Fatigue Profile of Prepubertal and Adult Female Handball Players.Sports (Basel, Switzerland) · 2025Article
- Development of juvenile sprint performance in boys: analysis of speed phases-a cross-sectional study by age.Frontiers in sports and active living · 2025Article
- A Modular Mathematical Model of Exercise-Induced Changes in Metabolism, Signaling, and Gene Expression in Human Skeletal Muscle.International journal of molecular sciences · 2021Article
- A thermodynamic function of glycogen in brain and muscle.Progress in neurobiology · 2020Article
- Plantar flexor muscle-tendon unit length and stiffness do not influence neuromuscular fatigue in boys and men.European journal of applied physiology · 2020Article
- Eccentric Resistance Training in Youth: Perspectives for Long-Term Athletic Development.Journal of functional morphology and kinesiology · 2019Review
- Exercise-induced fatigue in young people: advances and future perspectives.European journal of applied physiology · 2018Review
- Metabolic and Fatigue Profiles Are Comparable Between Prepubertal Children and Well-Trained Adult Endurance Athletes.Frontiers in physiology · 2018Article
- Are Prepubertal Children Metabolically Comparable to Well-Trained Adult Endurance Athletes?Sports medicine (Auckland, N.Z.) · 2017Review
- [High-intensity interval training for young athletes].Wiener medizinische Wochenschrift (1946) · 2014Review
- The rate of PCr resynthesis is not a reliable index of skeletal muscle oxidative capacity.European journal of applied physiology · 2014Article
- Reply to: The rate of PCr resynthesis is not a reliable index of skeletal muscle oxidative capacity.European journal of applied physiology · 2014Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the present study was to test the hypotheses that a greater oxidative capacity in children results in a lower phosphocreatine (PCr) depletion, a faster PCr resynthesis and a lower muscle acidification during high-intensity intermittent exercise compared to adults.
methodsSixteen children (9.4 ± 0.5 years) and 16 adults (26.1 ± 0.3 years) completed a protocol consisting of a dynamic plantar flexion (10 bouts of 30-s exercise at 25 % of one repetition maximum separated by 20-s recovery), followed by 10 min of passive recovery. Changes of PCr, ATP, inorganic phosphate, and phosphomonoesters were measured by means of (31)Phosphorous-magnetic resonance spectroscopy during and post-exercise.
resultsAverage PCr (percentage of [PCr] at initial rest (%[PCr]i)) at the end of the exercise (adults 17 ± 12 %[PCr]i, children 38 ± 17 %[PCr]i, P < 0.01) and recovery periods (adults 37 ± 14 %[PCr]i, children 57 ± 17 %[PCr]i, P < 0.01) was significantly lower in adults compared to children, induced by a stronger PCr decrease during the first exercise interval (adults -73 ± 10 %[PCr]i, children -55 ± 15 %[PCr]i, P < 0.01). End-exercise pH was significantly higher in children compared to adults (children 6.90 + 0.20, -0.14; adults 6.67 + 0.23, -0.15, P < 0.05).
conclusionsFrom our results we suggest relatively higher rates of oxidative ATP formation in children's muscle for covering the ATP demand of high-intensity intermittent exercise compared to adults, enabling children to begin each exercise interval with significantly higher PCr concentrations and leading to an overall lower muscle acidification.
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