Evidence map›Paper›PMID 23994864›Full record

ArticleJournal of epidemiology2013

Epidemiologic methods of assessing asthma and wheezing episodes in longitudinal studies: measures of change and stability.

Nelís Soto-Ramírez, Ali H Ziyab, Wilfried Karmaus, Hongmei Zhang, Ramesh J Kurukulaaratchy, Susan Ewart, Syed Hasan Arshad

Open access · goldAbstract read
In one paragraph

Article in Journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association of psoriasis with allergic multimorbidity of asthma, rhinitis, and eczema among adolescents: a cross-sectional study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Article
  5. Article
  6. Sex-specific developmental trajectories of eczema from infancy to age 26 years: A birth cohort study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Article
  7. Article
  8. Article
  9. Sex-specific associations of asthma acquisition with changes in DNA methylation during adolescence.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Breastfeeding duration modifies the effect of smoking during pregnancy on eczema from early childhood to adolescence.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2018
    Article
  15. Observational
  16. Observational
  17. Article
  18. Filaggrin mutations increase allergic airway disease in childhood and adolescence through interactions with eczema and aeroallergen sensitization.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2018
    Article
  19. Polycyclic aromatic hydrocarbons exposure, oxidative stress, and asthma in children.International archives of occupational and environmental health · 2017
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nelís Soto-RamírezDivision of Epidemiology, Biostatistics, and Environmental Health, University of Memphis.
Ali H Ziyab
Wilfried Karmaus
Hongmei Zhang
Ramesh J Kurukulaaratchy
Susan Ewart
Syed Hasan Arshad
David Hide Asthma and Allergy Research Centre · GBUniversity of South Carolina · USMichigan State University · USUniversity of Memphis · US

Funding

Transgenerational epigenetic inheritance of allergy in a multigenerational cohortR01AI091905 · NIAID · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARMAUS, WILFRIED JJ · 2011 to 2015
$2.7M
Genetic &epidemiologic cohort study of asthma &allergyR01AI061471 · NIAID · MICHIGAN STATE UNIVERSITY · PI EWART, SUSAN L · 2005 to 2009
$1.8M
Epidemiology of asthma: risk and prognosis in a cohort from birth to adolescenceR01HL082925 · NHLBI · ST. MARY'S HOSPITAL NEWPORT · PI ARSHAD, SYED HASAN · 2007 to 2010
$1.7M
NHLBI NIH HHS R01 HL082925NIAID NIH HHS R01 AI061471NIAID NIH HHS R01 AI091905
6 · The paper itself

Abstract

backgroundIn settings in which diseases wax and wane, there is a need to measure disease dynamics in longitudinal studies. Traditional measures of disease occurrence (eg, cumulative incidence) do not address change or stability or are limited to stable cohorts (eg, incidence) and may thus lead to erroneous conclusions. To illustrate how different measures can be used to detect disease dynamics, we investigated sex differences in the occurrence of asthma and wheezing, using a population-based study cohort that covered the first 18 years of life.

methodsIn the Isle of Wight birth cohort (n = 1456), prevalence, incidence, cumulative incidence, positive and negative transitions, and remission were determined at ages 1 or 2, 4, 10, and 18 years. Latent transition analysis was used to simultaneously identify classes of asthma and wheezing (related phenotypes) and characterize transition probabilities over time. Trajectory analysis was used to characterize the natural history of asthma and wheezing.

resultsRegarding time-specific changes, positive and negative transition probabilities were more informative than other measures of associations because they revealed a sex switchover in asthma prevalence (P < 0.05). Transition probabilities were able to identify the origin of a sex-specific dynamic; in particular, prior wheezing transitioned to asthma at age 18 years among girls but not among boys. In comparison with latent transition analysis, trajectory analysis did not directly identify a switchover in prevalence among boys and girls.

conclusionsIn longitudinal analyses, transition analyses that impose minimal restrictions on data are needed in order to produce appropriate information on disease dynamics.

Indexed as

AdolescentAsthmaChildChild, PreschoolEpidemiologic MethodsFemaleHumansIncidenceInfantLongitudinal StudiesMalePrevalenceRespiratory SoundsSex DistributionUnited Kingdom

Identifiers

PMID23994864
PMCPMC3834276
OpenAlexW2089112279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.