Evidence map›Paper›PMID 23994316›Full record

Trial reportNeuroImage2014

The neural mechanisms underlying internally and externally guided task selection.

Joseph M Orr, Marie T Banich

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Pooled it
  6. The role of the striatum in effort-based decision-making in the absence of reward.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
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  11. Enhancing free choice masked primingFrontiers in psychology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph M OrrInstitute of Cognitive Science, University of Colorado Boulder, USA. Electronic address: Joseph.Orr@colorado.edu.
Marie T Banich

Funding

Proj 5: Early Development (224-250)P50MH079485 · NIMH · UNIVERSITY OF COLORADO · PI MUNAKATA, YUKO · 2008 to 2012
$8.7M
Organization and timecourse of the neural mechanisms for cognitive flexibilityF32DA034412 · NIDA · UNIVERSITY OF COLORADO · PI ORR, JOSEPH M. · 2013 to 2015
$122k
NIDA NIH HHS 1-F32-DA034412-01A1NIDA NIH HHS F32 DA034412NIMH NIH HHS P50 MH079485PHS HHS P50 079485
6 · The paper itself

Abstract

While some prior work suggests that medial prefrontal cortex (MFC) regions mediate freely chosen actions, other work suggests that the lateral frontal pole (LFP) is responsible for control of abstract, internal goals. The present study uses fMRI to determine whether the voluntary selection of a task in pursuit of an overall goal relies on MFC regions or the LFP. To do so, we used a modified voluntary task switching (VTS) paradigm, in which participants choose an individual task to perform on each trial (i.e., a subgoal), under instructions to perform the tasks equally often and in a random order (i.e. the overall goal). In conjunction, we examined patterns of activation in the face of irrelevant, but task-related external stimuli that might nonetheless influence task selection. While there was some evidence that the MFC was involved in voluntary task selection, we found that the LFP and anterior insula (AI) were crucial to task selection in the pursuit of an overall goal. In addition, activation of the LFP and AI increased in the face of environmental stimuli that might serve as an interfering or conflicting external bias on voluntary task choice. These findings suggest that the LFP supports task selection according to abstract, internal goals, and leaves open the possibility that MFC may guide action selection in situations lacking in such top-down biases. As such, the current study represents a critical step towards understanding the neural underpinnings of how tasks are selected voluntarily to enable an overarching goal.

Indexed as

Task Performance and AnalysisBrain MappingChoice BehaviorCuesFemaleGoalsHumansMagnetic Resonance ImagingMaleMotivationPrefrontal CortexVolitionYoung AdultCognitive flexibilityExecutive functionfMRIGoal maintenanceVolition

Identifiers

PMID23994316
PMCPMC3849139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.