ArticleThe Journal of surgical research2014
Patterns of use of hemostatic agents in patients undergoing major surgery.
Article in The Journal of surgical research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05369988 (VALIDATION OF THE VIBe INTRAOPERATIVE BLEEDING SCALE IN LIVER SURGERY. PROSPECTIVE AND MULTICENTRIC STUDY), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
VALIDATION OF THE VIBe INTRAOPERATIVE BLEEDING SCALE IN LIVER SURGERY. PROSPECTIVE AND MULTICENTRIC STUDY
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Haemostatic Efficacy of Topical Agents During Liver Resection: A Network Meta-Analysis of Randomised Trials.World journal of surgery · 2020Pooled it
- Systematic Review of Topical Hemostatic Agent Use in Minimally Invasive Gynecologic Surgery.JSLS : Journal of the Society of Laparoendoscopic SurgeonsPooled it
- Trial
- A Study of Safety and Effectiveness of Evicel Fibrin Sealant as an Adjunctive Hemostat in Pediatric Surgery.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2024Trial
- Safety and Hemostatic Effectiveness of SURGICEL® Powder in Mild and Moderate Intraoperative Bleeding.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisTrial
- Efficacy and Safety of a Bioinspired Chitosan-Catechol/Gelatin Hemostatic Patch vs. TachoSil in Hepatectomy: A Randomized Noninferiority Trial.Biomedicines · 2026Article
- Surgical Determinants of Outcomes in Partial Nephrectomy: a Contemporary Review.Current urology reports · 2026Review
- Evaluation of the Performance of StypCelMedicina (Kaunas, Lithuania) · 2025Article
- Damage Control Surgery in Obstetrics and Gynecology: Abdomino-Pelvic Packing in Multimodal Hemorrhage Management.Journal of clinical medicine · 2025Review
- Implementation of a Cost and Variation Reduction Program for Hemostasis Products at a Large Academic Medical Center: A Multi-Stakeholder Perspective.Medical devices (Auckland, N.Z.) · 2025Article
- Gelatin-based biomaterials and gelatin as an additive for chronic wound repair.Frontiers in pharmacology · 2024Review
- Comparison of a gelatin thrombin versus a modified absorbable polymer as a unique treatment for severe hepatic hemorrhage in swine.Scientific reports · 2023Article
- Evaluation of the validated intraoperative bleeding scale in liver surgery: study protocol for a multicenter prospective study.Frontiers in surgery · 2023Article
- Evaluating the risk of post-operative abscess formation following use of hemostatic agents at time of hysterectomy.Gynecologic oncology reports · 2022Article
- Tranexamic acid-loaded hemostatic nanoclay microsphere frameworks.Journal of biomedical materials research. Part B, Applied biomaterials · 2022Article
- Biological compatibility of oxidized cellulose vs. porcine gelatin to control bleeding in liver lesions in rats.Acta cirurgica brasileira · 2022Article
- Advances in the development of hemostatic biomaterials for medical application.Biomaterials research · 2021Review
- An international multidisciplinary peer-driven consensus on the optimal use of hemostatic powders in surgical practice.Updates in surgery · 2021Article
- Comparison of the efficacy of five standard topical hemostats: a study in porcine liver and spleen models of surgical bleeding.BMC surgery · 2020Article
- Traumastem Powder in Treatment of Non-Traumatic Anterior Epistaxis in Emergency Department; a Randomized Clinical Trial.Archives of academic emergency medicine · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundAlthough a number of prohemostatic agents that are applied intraoperatively have been introduced to minimize bleeding, little is known about the patterns of use and the factors that influence use. We examined the use of hemostatic agents in patients undergoing major surgery.
methodsAll patients who underwent major general, gynecologic, urologic, cardiothoracic, or orthopedic surgery from 2000-2010 who were recorded in the Perspective database were analyzed.
resultsAmong 3,633,799 patients, hemostatic agents were used in 30.3% (n = 1,102,267). The use of hemostatic agents increased from 28.5% in 2000 to 35.2% in 2010. Over the same period, the rates of transfusion declined for pancreatectomy (-14.4%), liver resection (-15.0%), gastrectomy (-11.7%), prostatectomy (-6.6%), nephrectomy (-4.6%), hip arthroplasty (-10.4%), and knee arthroplasty (-6.6%). Over the same time period, the transfusion rate increased for colectomy (6.0%), hysterectomy (3.7%), coronary artery bypass graft (8.4%), valvuloplasty (4.2%), lung resection (1.9%), and spine surgery (1.6%). Transfusion remained relatively stable for thyroidectomy (0.2%).
conclusionsThe use of hemostatic agents has increased rapidly even for surgeries associated with a small risk of transfusion and bleeding complications. In addition to patient characteristics, surgeon and hospital factors exerted substantial influence on the allocation of hemostatic agents.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.