Evidence map›Paper›PMID 23992762›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2014

Substance use and sexual intercourse onsets in adolescence: a genetically informative discordant twin design.

Arielle R Deutsch, Wendy S Slutske, Andrew C Heath, Pamela A F Madden, Nicholas G Martin

Open access · bronzeAbstract readTwin Study
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Arielle R DeutschDepartment of Psychological Sciences, University of Missouri-Columbia, Columbia, Missouri; Midwest Alcohol Research Center, Columbia, Missouri. Electronic address: arielle.deutsch@gmail.com.
Wendy S SlutskeDepartment of Psychological Sciences, University of Missouri-Columbia, Columbia, Missouri; Midwest Alcohol Research Center, Columbia, Missouri.
Andrew C HeathMidwest Alcohol Research Center, Columbia, Missouri; Department of Psychiatry, Washington University, St. Louis, Missouri.
Pamela A F MaddenMidwest Alcohol Research Center, Columbia, Missouri; Department of Psychiatry, Washington University, St. Louis, Missouri.
Nicholas G MartinQueensland Institute of Medical Research, Brisbane, Australia.
Midwest Cardiovascular Research Foundation · USQIMR Berghofer Medical Research Institute · AUWashington University in St. Louis · US

Funding

Genetic Epideniologic Models of Alcohol AbuseR37AA007728 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1998 to 2007
$2.2M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
NIAAA NIH HHS K05 AA017688NIAAA NIH HHS R37 AA007728
6 · The paper itself

Abstract

purposeUsing a genetically informed, discordant twin analysis, the objective of this study was to examine whether earlier onset of drinking and smoking behaviors predicted early sexual intercourse onset.

methodsOver 3,400 adult same-sex twins from the Australian Twin Registry completed a structured interview that included retrospective reports on onsets of smoking, drinking, intoxication, and sexual intercourse and conduct disorder symptoms. A two-level frailty model estimated within-twin-pair and between-twin-pair comparisons. Onsets of smoking, drinking, drunkenness, and conduct disorder symptoms were estimated as sexual intercourse onset predictors.

resultsAfter controlling for conduct disorder, smoking and drinking onset did not predict sexual intercourse onset for either within-twin-pair or between-twin-pair comparisons. Drunkenness onset had a significant effect on sexual intercourse onset, such that twins who first experienced alcohol intoxication at a younger age than their co-twins were also more likely to have sex earlier than their co-twins.

conclusionsRelationships between substance use and sexual intercourse onsets may be due mostly to shared underlying factors; there was only a small relation between intoxication onset and sexual intercourse onset, and no direct relation between smoking and drinking onset and sexual intercourse onset.

Indexed as

CoitusSubstance-Related DisordersAdultAge of OnsetAlcoholic IntoxicationFemaleHumansMaleRetrospective StudiesRisk FactorsSmokingTwinsProblem behavior theorySexual intercourse onsetSubstance use onsetTwin study

Identifiers

PMID23992762
PMCPMC3872214
OpenAlexW2157969695

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.