ArticleActa orthopaedica2013
The decline in joint replacement surgery in rheumatoid arthritis is associated with a concomitant increase in the intensity of anti-rheumatic therapy: a nationwide register-based study from 1995 through 2010.
Article in Acta orthopaedica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 100 citations in OpenAlex.
- Long-Term Clinical and Radiological Outcomes of Cementless Total Knee Arthroplasty in Patients with Rheumatoid Arthritis.Journal of clinical medicine · 2026Article
- Changing Patterns of Hospitalisation and Orthopaedic Procedure Profiles in Major Inflammatory Rheumatic Diseases in Germany: a Nationwide Analysis of Hospital Discharge Data.Rheumatology international · 2026Article
- The Efficacy of Povidone-Iodine in Eradicating Staphylococcus aureus Biofilm on Stainless Steel Alloy Implants.Malaysian orthopaedic journal · 2026Article
- Review
- Surgical treatment of rheumatoid arthritis of the elbow.Journal of rheumatic diseases · 2025Review
- The moderating role of negative affect on pain in patients with rheumatoid arthritis who have undergone shoulder arthroplasty.Journal of orthopaedic surgery and research · 2025Article
- Global research trends and hotspots in rheumatoid arthritis joint replacement:Bibliometric analysis and visualization study.Journal of orthopaedics · 2025Review
- Biological Agent and Total Hip Arthroplasty in Rheumatoid Arthritis.Hip & pelvis · 2024Article
- The Challenges of Local Intra-Articular Therapy.Medicina (Kaunas, Lithuania) · 2024Review
- Is popularity of total elbow arthroplasty in the United States decreasing? An analysis of trends, demographics, and indications.JSES reviews, reports, and techniques · 2024Article
- Article
- Changes in knee joint destruction patterns among patients with rheumatoid arthritis undergoing total knee arthroplasty in recent decades.Clinical rheumatology · 2023Article
- Joint Replacement Surgery in Patients with Rheumatoid Arthritis in South Korea: Analysis of a Large National Database.Clinics in orthopedic surgery · 2023Article
- Projecting direct medical costs and productivity benefits of improving access to advanced therapy for rheumatoid arthritis: a projection modelling study.Journal of market access & health policy · 2023Article
- Trends in Total Joint Arthroplasty Among Patients With Rheumatoid Arthritis: The Effect of Recent Disease Modifying Antirheumatic Drug Utilization Guidelines.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Increasing trend of radiographic features of knee osteoarthritis in rheumatoid arthritis patients before total knee arthroplasty.Scientific reports · 2022Article
- Trends in the Utilization of Ankle Replacements: Data From Worldwide National Joint Registries.Foot & ankle international · 2021Article
- Opposing Trends in Total Knee and Hip Arthroplasties for Patients With Rheumatoid Arthritis vs. the General Population-A 14-Year Retrospective Study in Taiwan.Frontiers in medicine · 2021Article
- Incidence and Complication Rates for Total Hip Arthroplasty in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis Across Four Decades.Rheumatology and therapy · 2020Review
- Serum progranulin level is associated with disease activity following orthopedic surgery in rheumatoid arthritis patients.The Journal of international medical research · 2020Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDrug-based treatment of rheumatoid arthritis (RA) has evolved markedly over the past 2 decades. Using nationwide register data, we studied how this has affected the rates of hip, knee, shoulder, and elbow replacement from 1995 to 2010.
methodsThe number of primary joint replacements was obtained from the Finnish Arthroplasty Register. To test the hypothesis that improvements in medical treatment of RA reduce the need for joint replacements, we also collected data about purchases of different disease-modifying anti-rheumatic agents (DMARDs) and biological drugs from the nationwide drug registers.
resultsThe annual incidence of primary joint replacements for RA declined from 19 per 10(5) in 1995 to 11 per 10(5) in 2010. The decline was greater for upper-limb operations than for lower-limb operations. At the same time, the numbers of individuals using methotrexate, hydroxychloroquine, and sulfasalazine (the most commonly used DMARDs) increased 2- to 4-fold.
interpretationOur results are in accordance with observations from other countries, and indicate that the use of joint replacements in RA has decreased dramatically. Our data suggest that effective medical therapy is the most likely explanation for this favorable development.
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