ArticleJournal of thoracic disease2013
Epigenetic aberrant methylation of tumor suppressor genes in small cell lung cancer.
Article in Journal of thoracic disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Arsenic disulfide promoted the demethylation ofPeerJ · 2024Article
- Article
- Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions.Clinical epigenetics · 2018Article
- Retractions in cancer research: a systematic survey.Research integrity and peer review · 2017Article
- [Molecular pathology of lung cancer. State of the art 2014].Der Pathologe · 2014Review
- Study of epigenetic properties of Poly(HexaMethylene Biguanide) hydrochloride (PHMB).International journal of environmental research and public health · 2014Article
- Diabetes mellitus increases postoperative mortality in non-small cell lung cancer.Thoracic cancer · 2014Article
Corrections and comments
- Retraction · 2014-02-01Nonpayment of Fees and/or Refusal to Pay · Notice - Limited or No Information · · see author's comment on post:https://retractionwatch.com/2014/03/13/why-was-that-lung-cancer-paper-retracted-the-authors-reason-of-course/#comment-1577395
- Retracted
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Small cell lung cancer (SCLC), a special type of lung cancer, is reputed to carry a poor prognosis. The morbidity of SCLC is increasing in China and other countries. A variety of DNA alterations associated with non-small cell lung cancer (NSCLC) have been described. However, genetic and epigenetic changes of SCLC are not well established. Few studies have demonstrated that epigenetic silencing of key tumor suppressor genes (TSGs) is pivotal to initiation and development of SCLC. Recently, promoter methylation of many TSGs have been identified in SCLC. These novel TSGs are potential tumor biomarkers for early diagnosis and prognostic prediction. Moreover, epigenetic promoter methylation of TSGs could be a target of intervention with a wide prospect of clinical application. This review summarizes recent studies on promoter methylation of TSGs in SCLC and aims to provide better understanding of the promoter methylation in tumorigenesis and progression of SCLC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.