ArticleMicrobial ecology in health and disease2012
The gut: a triggering place for autism - possibilities and challenges.
Article in Microbial ecology in health and disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- The Microbiota in the Diagnosis and Treatment of Autism Spectrum Disorder.International journal of molecular sciences · 2026Review
- The association of vitamin A, zinc and copper levels with clinical symptoms in children with autism spectrum disorders in Jilin Province, China.BMC pediatrics · 2023Article
- Oxidative stress indices in ASD children in Sub-Sahara Africa.Journal of neurodevelopmental disorders · 2021Article
- Article
- Urinary Essential Elements of Young Children with Autism Spectrum Disorder and their Mothers.Research in autism spectrum disorders · 2020Article
- Gastrointestinal dysfunction in autism spectrum disorder: the role of the mitochondria and the enteric microbiome.Microbial ecology in health and disease · 2015Article
- Manipulating the gut microbiota to maintain health and treat disease.Microbial ecology in health and disease · 2015Article
- Prokaryotes Versus Eukaryotes: Who is Hosting Whom?Frontiers in veterinary science · 2014Review
- Editorial: The gut and the brain - with focus on autism spectrum disorders.Microbial ecology in health and disease · 2012Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring the recent years, a substantial amount of new data has underlined the importance of the gut as a triggering place for autism. Temporary improvements in clinical status following dietary alterations and the same that may occur after an antibiotic therapy are reported. Additionally, increasing numbers of bacteria belonging to certain groups, such as clostridia, desulfovibrios, and sutterella, have been reported. So far, however, presence of any bacterial group has never been causatively linked to autism, and every time a new candidate organism is introduced the same questions have to be asked: What is the cause? What is the consequence? What is the confounder? The possibilities of answering these questions are hampered by difficulties in obtaining adequate samples. Therefore, more efforts have been made to those biochemical methods that probe possible functional alterations in the gastrointestinal (GI) microbiota in autistic children.
conclusionAutism is a disorder involving many organs and their functions, including the GI microbiota. More knowledge about the GI microbiota and its cross-talks with the host creates possibilities for future diagnostic and therapeutic improvements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.