Evidence map›Paper›PMID 23990412›Full record

ArticleBioinformatics (Oxford, England)2013

Bayesian consensus clustering.

Eric F Lock, David B Dunson

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed.

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  4. CSIE: cancer subtyping via inference and ensemble.Briefings in bioinformatics · 2026
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  8. Integrative Analysis of Multimodal Omics Data.Annual review of statistics and its application · 2026
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  14. Design, processing, and modeling for longitudinal multiomics microbiome data.Frontiers in cellular and infection microbiology · 2026
    Review
  15. Article
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  17. Article
  18. Article
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  20. Article

91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric F LockDepartment of Statistical Science, Duke University, Durham, NC 27708, USA and Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA.
David B Dunson

Funding

Bayesian Methods for Assessing Gene by Environment InteractionsR01ES017436 · NIEHS · DUKE UNIVERSITY · PI DUNSON, DAVID BRIAN · 2009 to 2013
$1.7M
NIEHS NIH HHS R01-ES017436
6 · The paper itself

Abstract

motivationIn biomedical research a growing number of platforms and technologies are used to measure diverse but related information, and the task of clustering a set of objects based on multiple sources of data arises in several applications. Most current approaches to multisource clustering either independently determine a separate clustering for each data source or determine a single 'joint' clustering for all data sources. There is a need for more flexible approaches that simultaneously model the dependence and the heterogeneity of the data sources.

resultsWe propose an integrative statistical model that permits a separate clustering of the objects for each data source. These separate clusterings adhere loosely to an overall consensus clustering, and hence they are not independent. We describe a computationally scalable Bayesian framework for simultaneous estimation of both the consensus clustering and the source-specific clusterings. We demonstrate that this flexible approach is more robust than joint clustering of all data sources, and is more powerful than clustering each data source independently. We present an application to subtype identification of breast cancer tumor samples using publicly available data from The Cancer Genome Atlas. AVAILABILITY: R code with instructions and examples is available at http://people.duke.edu/%7Eel113/software.html.

Indexed as

AlgorithmsBayes TheoremCluster AnalysisGene DosageGenomicsHumansModels, Statistical

Identifiers

PMID23990412
PMCPMC3789539

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.