Evidence map›Paper›PMID 23989722›Full record

ReviewMolecular biology of the cell2013

The physical chemistry of cytoplasm and its influence on cell function: an update.

Kate Luby-Phelps

Abstract readReview
In one paragraph

Review in Molecular biology of the cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Supramolecular Gels as Active Tools for Reaction Engineering.Angewandte Chemie (International ed. in English) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Molecular Crowding: Physiologic Sensing and Control.Annual review of physiology · 2024
    Review
  16. Article
  17. How it feels in a cell.Trends in cell biology · 2023
    Review
  18. Article
  19. Review
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kate Luby-PhelpsDepartment of Cell Biology, UT Southwestern Medical School, Dallas, TX 75390, USA. kate.phelps@utsouthwestern.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From the point of view of intermolecular interactions, the cytoplasmic space is more like a crowded party in a house full of furniture than a game of tag in an empty field. Understanding the physical chemical properties of cytoplasm is thus of key importance for understanding cellular function. This article attempts to provide an entrée into the current literature on this subject and offers some general guidelines for thinking about intracellular biochemistry.

Indexed as

Cell Physiological PhenomenaCell SizeChemical PhenomenaCytoplasmDiffusionMacromolecular SubstancesSignal TransductionMacromolecular Substances

Identifiers

PMID23989722
PMCPMC3756912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.