ReviewJournal of women's health (2002)2013
Challenging and complex decisions in the management of the BRCA mutation carrier.
Review in Journal of women's health (2002), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Research status and hotspots of oncology genetic nursing: a bibliometric analysis.Frontiers in oncology · 2025Pooled it
- Review
- Short-term Impact of Hormone Replacement Therapy on Risk of Breast Cancer in BRCA Mutation Carriers: A Nationwide Study in South Korea.Cancer research and treatment · 2024Article
- Hereditary Ovarian Cancer: Towards a Cost-Effective Prevention Strategy.International journal of environmental research and public health · 2022Review
- What do women at high risk of breast cancer request of a patient education day? Focus interviews with women before and after deciding about prophylactic interventions.European journal of cancer care · 2022Article
- Management of patients with BRCA mutation from the point of view of a breast surgeon.Annals of medicine and surgery (2012) · 2021Review
- Article
- Development and Testing of a Decision Aid for Unaffected Women with a BRCA1 or BRCA2 Mutation.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020Article
- Precision prophylaxis: Identifying the optimal timing for risk-reducing salpingo-oophorectomy based on type of BRCA1 and BRCA2 cluster region mutations.Gynecologic oncology · 2020Article
- Interventions to improve psychosocial well-being in female BRCA-mutation carriers following risk-reducing surgery.The Cochrane database of systematic reviews · 2019Review
- Concerns and Expectations of Risk-Reducing Surgery in Women with Hereditary Breast and Ovarian Cancer Syndrome.Journal of clinical medicine · 2019Article
- Risks of breast or ovarian cancer in BRCA1 or BRCA2 predictive test negatives: findings from the EMBRACE study.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Cell Origins of High-Grade Serous Ovarian Cancer.Cancers · 2018Review
- Decision making for breast cancer prevention among women at elevated risk.Breast cancer research : BCR · 2017Review
- Identification and management of women with a family history of breast cancer: Practical guide for clinicians.Canadian family physician Medecin de famille canadien · 2016Review
- Review
- Ovarian Cancer and BRCA1/2 Testing: Opportunities to Improve Clinical Care and Disease Prevention.Frontiers in oncology · 2016Review
- Low-dose radiation risk and individual variation in radiation sensitivity in Fukushima.Journal of radiation research · 2016Article
- DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3.Journal of translational medicine · 2015Article
- Walking in the shoes of patients, not just in their genes: a patient-centered approach to genomic medicine.The patient · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Women afflicted by the hereditary breast and ovarian cancer syndrome face complex decisions regarding medical interventions aimed at reducing their risk of ovarian and breast cancer, interventions which in turn may interfere with their fertility and cause early menopause. This review addresses selected topics of importance and controversy in the management of the BRCA mutation carrier, such as psychological well-being and quality of life, breast and ovarian cancer screening, risk-reducing interventions for breast cancer and ovarian cancer, the issue of hysterectomy at the time of the risk-reducing salpingo-oophorectomy, health consequences of early surgical menopause, and safety of hormonal therapy after oophorectomy. The information presented is based on an extensive review of the literature on the selected topics and on the expertise of our multidisciplinary team.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.