Evidence map›Paper›PMID 23987509›Full record

ArticleDevelopmental cell2013

PRC2 goes solo in the Drosophila female germline.

Judith A Kassis, Mary A Lilly

Abstract readComment
In one paragraph

Article in Developmental cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Judith A KassisProgram in Genomics of Differentiation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. jkassis@mail.nih.gov
Mary A Lilly

Funding

Cell Cycle Regulation In OogenesisZIAHD001613 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI LILLY, MARY A · 2009 to 2025
$22.3M
Control Of Gene Expression During DevelopmentZIAHD005003 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI KASSIS, JUDITH ANN · 2009 to 2023
$16.4M
Intramural NIH HHS ZIA HD001613
6 · The paper itself

Abstract

Polycomb-group proteins silence gene expression through epigenetic modification of chromatin. In this issue of Developmental Cell, Iovino et al. (2013) demonstrate that Polycomb repressive complex 2 (PRC2) is required for maintenance of oocyte fate by repressing expression of two critical targets, Cyclin E and dacapo, during the early meiotic cycle.

Indexed as

Genes, cdcAnimalsCell LineageDrosophila melanogasterDrosophila ProteinsFemaleHistone-Lysine N-MethyltransferaseOocytesRepressor ProteinsDrosophila ProteinsHistone-Lysine N-MethyltransferasePRC2 protein, DrosophilaRepressor Proteins

Identifiers

PMID23987509
PMCPMC4772660

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.