Evidence map›Paper›PMID 23986746›Full record

ArticleFrontiers in endocrinology2013

Intersectin: The Crossroad between Vesicle Exocytosis and Endocytosis.

Olga Gubar, Dmytro Morderer, Lyudmila Tsyba, Pauline Croisé, Sébastien Houy, Stéphane Ory, Stéphane Gasman, Alla Rynditch

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2024
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  9. Alterations of presynaptic proteins in autism spectrum disorder.Frontiers in molecular neuroscience · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Intersectin scaffold proteins and their role in cell signaling and endocytosis.Biochimica et biophysica acta. Molecular cell research · 2017
    Review
  19. An Endocytic Scaffolding Protein together with Synapsin Regulates Synaptic Vesicle Clustering in the Drosophila Neuromuscular Junction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Olga GubarState Key Laboratory of Molecular and Cellular Biology, Institute of Molecular Biology and Genetics , Kyiv , Ukraine ; Department of Functional Genomics, Institute of Molecular Biology and Genetics , Kyiv , Ukraine ; Institut des Neurosciences Cellulaires et Intégratives, Centre National de la Recherche Scientifique-Unité Propre de Recherche 3212, Université de Strasbourg , Strasbourg , France.
Dmytro Morderer
Lyudmila Tsyba
Pauline Croisé
Sébastien Houy
Stéphane Ory
Stéphane Gasman
Alla Rynditch
Centre National de la Recherche Scientifique · FRInstitute of Molecular Biology and Genetics · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intersectins (ITSNs) are a family of highly conserved proteins with orthologs from nematodes to mammals. In vertebrates, ITSNs are encoded by two genes (itsn1 and itsn2), which act as scaffolds that were initially discovered as proteins involved in endocytosis. Further investigation demonstrated that ITSN1 is also implicated in several other processes including regulated exocytosis, thereby suggesting a role for ITSN1 in the coupling between exocytosis and endocytosis in excitatory cells. Despite a high degree of conservation amongst orthologs, ITSN function is not so well preserved as they have acquired new properties during evolution. In this review, we will discuss the role of ITSN1 and its orthologs in exo- and endocytosis, in particular in neurons and neuroendocrine cells.

Indexed as

Cdc42endocytosisexocytosisintersectinneuroendocrine cellsneuronsscaffold

Identifiers

PMID23986746
PMCPMC3753573
OpenAlexW1986084545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.