ArticleScientific reports2013
Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 102 citations in OpenAlex.
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- The circadian clock gene CYCLE as a potential target for disrupting blood-feeding behavior in the mosquito Culex pipiens.PLoS neglected tropical diseases · 2026Article
- Biting time of day in malaria mosquitoes is modulated by nutritional status.Malaria journal · 2025Article
- Biting time of day in malaria mosquitoes is modulated by nutritional status.bioRxiv : the preprint server for biology · 2025Article
- Parasite and vector circadian clocks mediate efficient malaria transmission.Nature microbiology · 2025Article
- Time-of-day changes in permethrin susceptibility and metabolic gene expression in Florida Aedes aegypti (Diptera: Culicidae).Journal of medical entomology · 2025Article
- Seasonal plasticity in daily timing of flight activity inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Intra-species quantification reveals differences in activity and sleep levels in the yellow fever mosquito, Aedes aegypti.Medical and veterinary entomology · 2024Article
- Aedes albopictus colonies from different geographic origins differ in their sleep and activity levels but not in the time of peak activity.Medical and veterinary entomology · 2024Article
- Rhythms in insect olfactory systems: underlying mechanisms and outstanding questions.The Journal of experimental biology · 2024Review
- Only incandescent light significantly decreases feeding of Anopheles funestus s.s. (Diptera: Culicidae) mosquitoes under laboratory conditions.Parasitology research · 2024Article
- Circadian and daily rhythms of disease vector mosquitoes.Current opinion in insect science · 2024Review
- Article
- Effects of circadian clock disruption on gene expression and biological processes in Aedes aegypti.BMC genomics · 2024Article
- Sleep: An Essential and Understudied Process in the Biology of Blood-Feeding Arthropods.Integrative and comparative biology · 2023Review
- Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target.Nature communications · 2023Article
- Mosquito host-seeking diel rhythm and chemosensory gene expression is affected by age and Plasmodium stages.Scientific reports · 2022Article
- No evidence for long-range male sex pheromones in two malaria mosquitoes.Nature ecology & evolution · 2022Article
- Quantitative Trait Locus Determining the Time of Blood Feeding in Culex pipiens (Diptera: Culicidae).Journal of medical entomology · 2022Article
- Behavioral and postural analyses establish sleep-like states for mosquitoes that can impact host landing and blood feeding.The Journal of experimental biology · 2022Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
We recently characterized 24-hr daily rhythmic patterns of gene expression in Anopheles gambiae mosquitoes. These include numerous odorant binding proteins (OBPs), soluble odorant carrying proteins enriched in olfactory organs. Here we demonstrate that multiple rhythmically expressed genes including OBPs and takeout proteins, involved in regulating blood feeding behavior, have corresponding rhythmic protein levels as measured by quantitative proteomics. This includes AgamOBP1, previously shown as important to An. gambiae odorant sensing. Further, electrophysiological investigations demonstrate time-of-day specific differences in olfactory sensitivity of antennae to major host-derived odorants. The pre-dusk/dusk peaks in OBPs and takeout gene expression correspond with peak protein abundance at night, and in turn coincide with the time of increased olfactory sensitivity to odorants requiring OBPs and times of increased blood-feeding behavior. This suggests an important role for OBPs in modulating temporal changes in odorant sensitivity, enabling the olfactory system to coordinate with the circadian niche of An. gambiae.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.