ArticleJournal of the Royal Society, Interface2013
What can information-asymmetric games tell us about the context of Crick's 'frozen accident'?
Article in Journal of the Royal Society, Interface, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- How Mitochondrial Signaling Games May Shape and Stabilize the Nuclear-Mitochondrial Symbiosis.Biology · 2024Article
- Do Place Cells Dream of Deceptive Moves in a Signaling Game?Neuroscience · 2023Review
- How signalling games explain mimicry at many levels: from viral epidemiology to human sociology.Journal of the Royal Society, Interface · 2021Article
- How Signaling Games Explain Mimicry at Many Levels: From Viral Epidemiology to Human Sociology.Research square · 2020Article
- Genetic Code Error Minimization as a Non-Adaptive But Beneficial Trait.Journal of molecular evolution · 2019Article
- Origin of biomolecular games: deception and molecular evolution.Journal of the Royal Society, Interface · 2018Article
- Genetic code evolution reveals the neutral emergence of mutational robustness, and information as an evolutionary constraint.Life (Basel, Switzerland) · 2015Article
- The natural history of transfer RNA and its interactions with the ribosome.Frontiers in genetics · 2014Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This paper describes a novel application of information-asymmetric (signalling) games to molecular biology in which utility is determined by the message complexity (rate) in addition to the error in information transfer (distortion). We show using a computational model how it is possible for the agents in one such game to evolve a signalling convention (separating equilibrium) that is suboptimal in terms of information transfer, but is nonetheless stable. In the context of an RNA world merging with a nascent amino acid one, such a game's equilibrium is alluded to by the genetic code, which is nearly optimal in terms of information transfer, but is also near-universal and nearly immutable. Such a framework suggests that cellularity may have emerged to encourage coordination between RNA species and sheds light on other aspects of RNA world biochemistry yet to be fully understood.
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Registered trials
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