Evidence map›Paper›PMID 23985301›Full record

ReviewParasitology2014

Open source drug discovery - a limited tutorial.

Murray N Robertson, Paul M Ylioja, Alice E Williamson, Michael Woelfle, Michael Robins, Katrina A Badiola, Paul Willis, Piero Olliaro, Timothy N C Wells, Matthew H Todd

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Parasitology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Is Open Science the Future of Drug Development?The Yale journal of biology and medicine · 2017
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Freeze-fracture investigation of the red pulp of human spleen.Virchows Archiv. B, Cell pathology including molecular pathology · 1989
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Murray N RobertsonSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Paul M YliojaSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Alice E WilliamsonSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Michael WoelfleSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Michael RobinsSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Katrina A BadiolaSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Paul WillisMedicines for Malaria Venture, PO Box 1826, 20 rte de Pré-Bois, 1215 Geneva 15, Switzerland.
Piero OlliaroUNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR), World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.
Timothy N C WellsMedicines for Malaria Venture, PO Box 1826, 20 rte de Pré-Bois, 1215 Geneva 15, Switzerland.
Matthew H ToddSchool of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Open science is a new concept for the practice of experimental laboratory-based research, such as drug discovery. The authors have recently gained experience in how to run such projects and here describe some straightforward steps others may wish to take towards more openness in their own research programmes. Existing and inexpensive online tools can solve many challenges, while some psychological barriers to the free sharing of all data and ideas are more substantial.

Indexed as

Drug DiscoverySoftwareAnthelminticsAntimalarialsDisclosureHumansInformation DisseminationInternetMalariaSchistosomiasisAnthelminticsAntimalarials

Identifiers

PMID23985301
PMCPMC3884843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.