Evidence map›Paper›PMID 23984442›Full record

ArticleNature structural & molecular biology2013

EMI1, a three-in-one ubiquitylation inhibitor.

Hiroyuki Yamano

Abstract readNewsComment
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The role of Fbxo5 in the development of human malignant tumors.American journal of cancer research · 2022
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Hiroyuki Yamano

Funding

Cancer Research UK 13586
6 · The paper itself

Abstract

The anaphase-promoting complex/cyclosome (APC/C) is restricted by metazoan protein early mitotic inhibitor 1 (EMI1), a natural, potent inhibitor. New findings suggest that the multimodal inhibitory mechanisms of EMI1 control APC/C-dependent ubiquitylation.

Indexed as

Anaphase-Promoting Complex-CyclosomeAntigens, CDCadherinsCell Cycle ProteinsF-Box ProteinsHumansUbiquitin-Protein Ligase ComplexesAnaphase-Promoting Complex-CyclosomeAntigens, CDCadherinsCDH1 protein, humanCell Cycle ProteinsF-Box ProteinsFBXO5 protein, humanUbiquitin-Protein Ligase Complexes

Identifiers

PMID23984442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.