SynthesisBioMed research international2013
Hemoglobin concentration and pregnancy outcomes: a systematic review and meta-analysis.
Synthesis in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- Association between anemia in pregnancy with low birth weight and preterm birth in Ethiopia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Maternal low and high hemoglobin concentrations and associations with adverse maternal and infant health outcomes: an updated global systematic review and meta-analysis.BMC pregnancy and childbirth · 2023Pooled it
- Maternal hemoglobin concentrations across pregnancy and maternal and child health: a systematic review and meta-analysis.Annals of the New York Academy of Sciences · 2019Pooled it
- Pooled it
- Trial
- Anaemia and iron deficiency in pregnancy and adverse perinatal outcomes in Southern India.European journal of clinical nutrition · 2020Trial
- Association between high maternal haemoglobin levels in the first trimester and gestational diabetes mellitus: a prospective birth cohort study.Journal of global health · 2026Article
- Haemoglobin Concentrations and Maternal and Neonatal Outcomes: Identifying Optimal Haemoglobin Ranges.Paediatric and perinatal epidemiology · 2026Article
- Machine learning-based risk assessment of neonatal perinatal adverse outcomes of anemia during pregnancy: a modeling study.BMC medical informatics and decision making · 2026Article
- Association of maternal longitudinal haemoglobin concentrations with adverse pregnancy outcomes: A prospective cohort study.Journal of global health · 2026Observational
- Changes in Maternal Hemoglobin Concentration and Risk of Low Birth Weight and Small-for-Gestational-Age in the United Arab Emirates: The Mutaba'ah Study.International journal of women's health · 2026Article
- Differential Effects of Gynecological and Chronological Age on Low Birth Weight and Small for Gestational Age.Biomedicines · 2025Article
- Effects of anaemia development during pregnancy on maternal psychological health.BMJ mental health · 2025Article
- Article
- The correlation between hemoglobin concentration and blood pressure during pregnancy in different trimesters.BMC pregnancy and childbirth · 2024Article
- Article
- Is It Time to Alter the Standard of Care for Iron Deficiency/Iron Deficiency Anemia in Reproductive-Age Women?Biomedicines · 2024Review
- Diagnostic accuracy of a non-invasive spot-check hemoglobin meter, Masimo Rad-67® pulse CO-Oximeter®, in detection of anemia in antenatal care settings in Kenya.Frontiers in global women's health · 2024Article
- Maternal risk factors for low birthweight and macrosomia: a cross-sectional study in Northern Region, Ghana.Journal of health, population, and nutrition · 2023Article
- The development of a prediction model for arrest of labour to be used at regular check-ups, during 36 or 37 gestational weeks, for primiparas: a retrospective cohort study.Archives of gynecology and obstetrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo conduct a systematic review and meta-analysis of hemoglobin effect on the pregnancy outcomes.
methodsWe searched MEDLINE and SCOPUS from January 1, 1990 to April 10, 2011. Observational studies addressing association between hemoglobin and adverse pregnancy outcomes were selected. Two reviewers independently extracted data. A mixed logistic regression was applied to assess the effects of hemoglobin on preterm birth, low birth weight, and small for gestational age.
resultsSeventeen studies were included in poolings. Hemoglobin below 11 g/dL was, respectively, 1.10 (95% CI: 1.02-1.19), 1.17 (95% CI: 1.03-1.32), and 1.14 (95% CI: 1.05-1.24) times higher risk of preterm birth, low birth weight, and small for gestational age than normal hemoglobin in the first trimester. In the third trimester, hemoglobin below 11 g/dL was 1.30 (95% CI: 1.08-1.58) times higher risk of low birth weight. Hemoglobin above 14 g/dL in third trimester decreased the risk of preterm term with ORs of 0.50 (95% CI: 0.26-0.97), but it might be affected by publication bias.
conclusionsOur review suggests that hemoglobin below 11 g/dl increases the risk of preterm birth, low birth weight, and small gestational age in the first trimester and the risk of low birth weight in the third trimester.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.