ArticleISRN allergy2013
The challenge of delivering therapeutic aerosols to asthma patients.
Article in ISRN allergy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Global pMDI Use and the Potential Impact of European PFAS Legislation on Access to These Essential Inhaled Medications.Pulmonary therapy · 2026Article
- Enhancing aerosol delivery in asthma and COPD: a comparison of MDI, valved holding chamber, and DPI systems using functional respiratory imaging (FRI).Scientific reports · 2026Article
- Pulmonary inhalation for disease treatment: Basic research and clinical translations.Materials today. Bio · 2024Review
- Inhaled Medicines for Targeting Non-Small Cell Lung Cancer.Pharmaceutics · 2023Review
- Technical Evaluation of Soft Mist Inhaler Use in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.International journal of chronic obstructive pulmonary disease · 2020Article
- The Projected Economic and Health Burden of Uncontrolled Asthma in the United States.American journal of respiratory and critical care medicine · 2019Article
- Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD.Pulmonary therapy · 2019Review
- Targeted Drug Delivery to Upper Airways Using a Pulsed Aerosol Bolus and Inhaled Volume Tracking Method.Flow, turbulence and combustion · 2019Article
- Single Inhaler LABA/LAMA for COPD.Frontiers in pharmacology · 2019Article
- Knowledge and practice of dry powder inhalation among patients with chronic obstructive pulmonary disease in a regional hospital, Nepal.International journal of general medicine · 2019Article
- The Use of Video Instructions in Patient Education Promoting Correct Technique for Dry Powder Inhalers: An Investigation on Inhaler-Naïve Individuals.Pharmacy (Basel, Switzerland) · 2018Article
- Objective Assessment of Patient Inhaler User Technique Using an Audio-Based Classification Approach.Scientific reports · 2018Article
- The Nurse Practitioners' Perspective on Inhaler Education in Asthma and Chronic Obstructive Pulmonary Disease.Canadian respiratory journal · 2018Review
- Optimizing the Delivery of Inhaled Medication for Respiratory Patients: The Role of Valved Holding Chambers.Canadian respiratory journal · 2018Review
- Improving the Efficiency of Respiratory Drug Delivery: A Review of Current Treatment Trends and Future Strategies for Asthma and Chronic Obstructive Pulmonary Disease.Pulmonary therapy · 2017Review
- Predictors of correct technique in patients using pressurized metered dose inhalers.BMC pulmonary medicine · 2017Article
- The Delivery of High-Dose Dry Powder Antibiotics by a Low-Cost Generic Inhaler.The AAPS journal · 2017Article
- Patients' perspectives and preferences in the choice of inhalers: the case for Respimat(®) or HandiHaler(®).Patient preference and adherence · 2016Review
- Pharmacokinetic studies for proving bioequivalence of orally inhaled drug products-critical issues and concepts.Frontiers in pharmacology · 2015Article
- Identify practice gaps in medication education through surveys to patients and physicians.Patient preference and adherence · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of people with asthma continues to grow around the world, and asthma remains a poorly controlled disease despite the availability of management guidelines and highly effective medication. Patient noncompliance with therapy is a major reason for poor asthma control. Patients fail to comply with their asthma regimen for a wide variety of reasons, but incorrect use of inhaler devices is amongst the most common. The pressurised metered-dose inhaler (pMDI) is still the most frequently used device worldwide, but many patients fail to use it correctly, even after repeated tuition. Breath-actuated inhalers are easier to use than pMDIs. The rationale behind inhaler choice should be evidence based rather than empirical. When choosing an inhaler device, it is essential that it is easy to use correctly, dosing is consistent, adequate drug is deposited in both central and peripheral airways, and that drug deposition is independent of airflow. Regular checking of inhalation technique is crucial, as correct inhalation is one of the cornerstones of successful asthma management.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.