Evidence map›Paper›PMID 23983387›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2012

Anti-diarrheal activity and toxicity of Learng Pid Samud recipe.

Seewaboon Sireeratawong, Parirat Khonsung, Urarat Nanna, Supaporn Vannasiri, Nirush Lertprasertsuke, Tipaya Singhalak, Noppamas Soonthornchareonnon, Kanjana Jaijoy

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In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Seewaboon SireeratawongDivision of Pharmacology, Department of Preclinical Science, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand. seewaboon@gmail.com
Parirat Khonsung
Urarat Nanna
Supaporn Vannasiri
Nirush Lertprasertsuke
Tipaya Singhalak
Noppamas Soonthornchareonnon
Kanjana Jaijoy
Chiang Mai University · THThammasat University · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Learng Pid Samud (LPS) recipe is a traditional remedy in Thai folk medicine to ease the common diarrhea. The anti-diarrheal potential of LPS recipe was herein examined in vitro using a guinea-pig ileum model. The LPS exerted an inhibitory effect on acetylcholine-induced smooth muscle contraction in the guinea pig ileum. Significantly, not only did the LPS reduce the total amount of feces in the induced diarrhea rats, but also the intestinal transit in the charcoal meal test. A single oral administration with the recipe at 5,000 mg/kg did not cause acute toxicity and the daily oral administration (1,000, 2,000 and 4,000 mg/kg) for 90 days in rats did not produce any toxic signs and symptoms. In conclusion, the Learng Pid Samud recipe remedy is evidently safe and effective for the anti-diarrheal treatment which supports its therapeutic uses in the alternative medicine.

Indexed as

Medicine, TraditionalPhytotherapyAnimalsCharcoalDefecationDiarrheaDisease Models, AnimalFecesFemaleGastrointestinal TransitGuinea PigsIleumMaleMuscle ContractionMuscle, SmoothPlant ExtractsCharcoalPlant ExtractsAcute toxicityAnti-diarrheal activityChronic toxicityLearng Pid Samud

Identifiers

PMID23983387
PMCPMC3746652
OpenAlexW1983559847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.