Evidence map›Paper›PMID 23983329›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2012

Adjuvant effects of Sijunzi decoction in chickens orally vaccinated with attenuated Newcastle-disease vaccine.

Dianxin Zhang, Wanyu Shi, Yantao Zhao, Xiuhui Zhong

Abstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dianxin ZhangDepartment of Animal science and Veterinary Medicine, Cangzhou Vocational College of Technology.
Wanyu Shi
Yantao Zhao
Xiuhui Zhong

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many Chinese Herbal medicines (CHMs) and their components have been reported to enhance immunity. In this study, the capacity for the Chinese herbal medicine, oral administration Sijunzi Decoction (SJZD) in stimulating Newcastle disease virus(NDV) immunity in chickens was examined. Serum was sampled on days 20, 30, 40, 50 and 60 and tissues were collected on days 20, 40 and 60, respectively. The immune responses were determined by means of hemagglutination inhibition test, immunohistochemistry examination and semi-quantitative RT-PCR. The results showed that SJZD could increase the antibody titers and the area coefficient of IgA secreting cells, promote the expression of IL-2 mRNA in the whole immune period and IFN-γ mRNA was increased in the initial stage. The SJZD used was safe with no adverse effects on chicken weight or survival, providing evidence for the use of SJZD as an oral adjuvant.

Indexed as

VaccinationAdjuvants, ImmunologicAdministration, OralAnimalsAtractylodesChickensDrugs, Chinese HerbalGlycyrrhizaImmunoglobulin AInterferon-gammaInterleukin-2Newcastle DiseaseNewcastle disease virusPanaxPoriaPoultry DiseasesAdjuvants, ImmunologicDrugs, Chinese HerbalImmunoglobulin AInterferon-gammaInterleukin-2RNA, MessengerAttenuated Newcastle-disease vaccineChickenmucosal immunity adjuvantSijunzi Decoction

Identifiers

PMID23983329
PMCPMC3746531

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.