ArticleAdvanced materials (Deerfield Beach, Fla.)2013
Biochemical and physical signal gradients in hydrogels to control stem cell behavior.
Article in Advanced materials (Deerfield Beach, Fla.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed.
- Millimeter-Scale Dual-Opposing RNA-Gradient Hydrogel for Interfacial Gene Silencing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- 3D Printing Strategies for Bioengineering Human Cornea.Advanced healthcare materials · 2026Review
- A technique to create hydrogels with tethered concentration gradients of moleculesSoft matter · 2026Article
- Three-Dimensional Bioprinting of Regenerative Cartilage Constructs with Directional Ionically Derived Stiffness Gradients.Journal of functional biomaterials · 2025Article
- Mesenchymal Stromal Cell Chondrogenic Differentiation Induced by Continuous Stiffness Gradient in Photocrosslinkable Hydrogels.Journal of biomedical materials research. Part A · 2025Article
- Integrating mechanical cues with engineered platforms to explore cardiopulmonary development and disease.iScience · 2023Review
- Integration of Extracellular Matrices into Organ-on-Chip Systems.Advanced healthcare materials · 2023Review
- Bioinspired gradient scaffolds for osteochondral tissue engineering.Exploration (Beijing, China) · 2023Review
- Stem cell-laden hydrogel bioink for generation of high resolution and fidelity engineered tissues with complex geometries.Bioactive materials · 2022Article
- Micropatterns and peptide gradient on the inner surface of a guidance conduit synergistically promotes nerve regenerationBioactive materials · 2022Article
- 4D biofabrication via instantly generated graded hydrogel scaffolds.Bioactive materials · 2022Article
- Measuring the Effects of Cytokines on the Modification of Pericellular Rheology by Human Mesenchymal Stem Cells.ACS biomaterials science & engineering · 2021Article
- Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges.Bioactive materials · 2021Review
- Reversible dynamic mechanics of hydrogels for regulation of cellular behavior.Acta biomaterialia · 2021Article
- Fabrication approaches for high-throughput and biomimetic disease modeling.Acta biomaterialia · 2021Review
- Heparin-modified alginate microspheres enhance neovessel formation in hiPSC-derived endothelial cells and heterocellular in vitro models by controlled release of vascular endothelial growth factor.Journal of biomedical materials research. Part A · 2021Article
- Cell-Laden Gradient Hydrogel Scaffolds for Neovascularization of Engineered Tissues.Advanced healthcare materials · 2021Article
- Gradient Hydrogels.Advances in biochemical engineering/biotechnology · 2021Article
- Functionally graded biomaterials for use as model systems and replacement tissues.Advanced functional materials · 2020Article
- Converting 2D Nanofiber Membranes to 3D Hierarchical Assemblies with Structural and Compositional Gradients Regulates Cell Behavior.Advanced materials (Deerfield Beach, Fla.) · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Three-dimensional (3D) gradients of biochemical and physical signals in macroscale degradable hydrogels are engineered that can regulate photoencapsulated human mesenchymal stem cell (hMSC) behavior. This simple, cytocompatible, and versatile gradient system may be a valuable tool for researchers in biomaterials science to control stem cell fate in 3D and guide tissue regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.