ArticleThe Journal of comparative neurology2014
Tonotopic organization of vertical cells in the dorsal cochlear nucleus of the CBA/J mouse.
Article in The Journal of comparative neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- A discrete serotonergic circuit involved in the generation of tinnitus behavior.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Identification and quantification of GABAIBRO neuroscience reports · 2025Article
- Fast Inhibition Slows and Desynchronizes Mouse Auditory Efferent Neuron Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Imaging Voltage Globally and in Isofrequency Lamina in Slices of Mouse Ventral Cochlear Nucleus.eNeuro · 2023Article
- The role of GABAFrontiers in endocrinology · 2023Review
- Differential projections from the cochlear nucleus to the inferior colliculus in the mouse.Frontiers in neural circuits · 2023Article
- Molecular mechanisms governing development of the hindbrain choroid plexus and auditory projection: A validation of the seminal observations of Wilhelm His.IBRO neuroscience reports · 2022Review
- Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus.eLife · 2020Article
- Neuronal population model of globular bushy cells covering unit-to-unit variability.PLoS computational biology · 2019Article
- Principal Neurons in the Anteroventral Cochlear Nucleus Express Cell-Type Specific Glycine Receptor α Subunits.Neuroscience · 2019Article
- Relationships between neuronal birthdates and tonotopic positions in the mouse cochlear nucleus.The Journal of comparative neurology · 2019Article
- A biophysical modelling platform of the cochlear nucleus and other auditory circuits: From channels to networks.Hearing research · 2018Article
- Saturation of long-term potentiation in the dorsal cochlear nucleus and its pharmacological reversal in an experimental model of tinnitus.Experimental neurology · 2017Article
- An Overrepresentation of High Frequencies in the Mouse Inferior Colliculus Supports the Processing of Ultrasonic Vocalizations.PloS one · 2015Article
- Transcutaneous induction of stimulus-timing-dependent plasticity in dorsal cochlear nucleus.Frontiers in systems neuroscience · 2015Article
- A map of functional synaptic connectivity in the mouse anteroventral cochlear nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The systematic and topographic representation of frequency is a first principle of organization throughout the auditory system. The dorsal cochlear nucleus (DCN) receives direct tonotopic projections from the auditory nerve (AN) as well as secondary and descending projections from other sources. Among the recipients of AN input in the DCN are vertical cells (also called tuberculoventral cells), glycinergic interneurons thought to provide on- or near-best-frequency feed-forward inhibition to principal cells in the DCN and various cells in the anteroventral cochlear nucleus (AVCN). Differing lines of physiological and anatomical evidence suggest that vertical cells and their projections are organized with respect to frequency, but this has not been conclusively demonstrated in the intact mammalian brain. To address this issue, we retrogradely labeled vertical cells via physiologically targeted injections in the AVCN of the CBA/J mouse. Results from multiple cases were merged with a normalized 3D template of the cochlear nucleus (Muniak et al. [2013] J. Comp. Neurol. 521:1510-1532) to demonstrate quantitatively that the arrangement of vertical cells is tonotopic and aligned to the innervation pattern of the AN. These results suggest that vertical cells are well positioned for providing immediate, frequency-specific inhibition onto cells of the DCN and AVCN to facilitate spectral processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.