ArticleHuman brain mapping2014
Evaluating the arcuate fasciculus with combined diffusion-weighted MRI tractography and electrocorticography.
Article in Human brain mapping, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- The Cortico-Cortical and Subcortical Circuits of the Human Brain Language Centers Including the Dual Limbic and Language Functioning Fiber Tracts.Brain sciences · 2026Review
- Towards a somatosensory theory of speech perception.Journal of neurophysiology · 2022Review
- Brain Imaging in Epilepsy-Focus on Diffusion-Weighted Imaging.Diagnostics (Basel, Switzerland) · 2022Review
- Frontotemporal phase lag index correlates with seizure severity in patients with temporal lobe epilepsy.Frontiers in neurology · 2022Article
- Chemotherapy-Induced Brain Effects in Small-Cell Lung Cancer Patients: A Multimodal MRI Study.Brain topography · 2021Article
- Correlation of language lateralization with resting state hippocampal connectivity in temporal lobe epilepsy patientsTurkish journal of medical sciences · 2020Article
- Breastfeeding Duration Is Associated with Regional, but Not Global, Differences in White Matter Tracts.Brain sciences · 2019Article
- Four-dimensional functional cortical maps of visual and auditory language: Intracranial recording.Epilepsia · 2019Article
- Neural dynamics of verbal working memory in auditory description naming.Scientific reports · 2018Article
- Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate fasciculus following music-cued motor training.Brain and cognition · 2017Article
- Spatio-temporal dynamics of working memory maintenance and scanning of verbal information.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2017Article
- Three- and four-dimensional mapping of speech and language in patients with epilepsy.Brain : a journal of neurology · 2017Article
- Electrocorticographic mapping of expressive language function without requiring the patient to speak: A report of three cases.Epilepsy & behavior case reports · 2016Article
- Resting-state functional connectivity predicts the strength of hemispheric lateralization for language processing in temporal lobe epilepsy and normals.Human brain mapping · 2015Article
- Article
- Evaluating signal-correlated noise as a control task with language-related gamma activity on electrocorticography.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2014Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
The conventional model of language-related brain structure describing the arcuate fasciculus as a key white matter tract providing a direct connection between Wernicke's region and Broca's area has been called into question. Specifically, the inferior precentral gyrus, possessing both primary motor (Brodmann Area [BA] 4) and premotor cortex (BA 6), has been identified as a potential alternative termination. The authors initially localized cortical sites involved in language using measurement of event-related gamma-activity on electrocorticography (ECoG). The authors then determined whether language-related sites of the temporal lobe were connected, via white matter structures, to the inferior frontal gyrus more tightly than to the precentral gyrus. The authors found that language-related sites of the temporal lobe were far more likely to be directly connected to the inferior precentral gyrus through the arcuate fasciculus. Furthermore, tractography was a significant predictor of frontal language-related ECoG findings. Analysis of an interaction between anatomy and tractography in this model revealed tractrography to have the highest predictive value for language-related ECoG findings of the precentral gyrus. This study failed to support the conventional model of language-related brain structure. More feasible models should include the inferior precentral gyrus as a termination of the arcuate fasciculus. The exact functional significance of direct connectivity between temporal language-related sites and the precentral gyrus requires further study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.