ArticleWorld journal of surgery2013
Hypothyroidism after hemithyroidectomy.
Article in World journal of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid: A Systematic Review and Meta-analysis.JAMA otolaryngology-- head & neck surgery · 2022Pooled it
- Prevalence of and risk factors for hypothyroidism after hemithyroidectomy: a systematic review and meta-analysis.Endocrine · 2020Pooled it
- Higher Post-Operative L-Thyroxine Dosage Needed After Right Compared to Left-Lobe Hemithyroidectomy.Endocrinology, diabetes & metabolism · 2026Article
- Incidence and risk factors for early thyroxin supplementation therapy after hemithyroidectomy for benign conditions in Europe. A Eurocrine® registry-based study.Updates in surgery · 2025Article
- Role of Preoperative Thyroid-Stimulating Hormone Levels in the Prediction of Thyroid Hormone Replacement after Hemithyroidectomy.International archives of otorhinolaryngology · 2025Article
- Hypothyroidism After Hemithyroidectomy: A Retrospective Analysis of Temporal Trends and Key Risk Factors.Journal of clinical medicine · 2025Article
- Association of obesity with orbital fat expansion in thyroid eye disease.BMC ophthalmology · 2025Observational
- Hypothyroidism after hemithyroidectomy: a systematic review and meta-analysis.Thyroid research · 2024Review
- Artificial Intelligence for Pre-operative Diagnosis of Malignant Thyroid Nodules Based on Sonographic Features and Cytology Category.World journal of surgery · 2023Article
- Time to Hypothyroidism Following Hemithyroidectomy.Cureus · 2022Article
- Radiofrequency ablation for symptomatic, non-functioning, thyroid nodules: a single-center learning curve.Endocrine connections · 2022Article
- Changes in Thyroid Antibodies after Microwave Ablation of Thyroid Nodules.International journal of endocrinology · 2022Article
- Predictive factors for hypothyroidy after hemithyroidectomy.F1000Research · 2022Article
- Correlation and agreement between superb micro-vascular imaging and contrast-enhanced ultrasound for assessing radiofrequency ablation treatment of thyroid nodules: a preliminary study.BMC medical imaging · 2021Article
- Risk factors for hypothyroidism and thyroid hormone replacement after hemithyroidectomy in papillary thyroid carcinoma.Langenbeck's archives of surgery · 2021Article
- Usefulness of 1-year of thyroid stimulating hormone suppression on additional levothyroxine in patients who underwent hemithyroidectomy with papillary thyroid microcarcinoma.Gland surgery · 2019Article
- Management of Subclinical and Overt Hypothyroidism Following Hemithyroidectomy in Children and Adolescents: A Pilot Study.Frontiers in pediatrics · 2019Article
- Controversies in the Management of Low-Risk Differentiated Thyroid Cancer.Endocrine reviews · 2017Review
- The Effect of Levothyroxine Discontinuation Timing on Postoperative Hypothyroidism after Hemithyroidectomy for Papillary Thyroid Microcarcinoma.International journal of endocrinology · 2016Article
- Prospective analysis of risk for hypothyroidism after hemithyroidectomy.International journal of endocrinology · 2015Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk of hypothyroidism after hemithyroidectomy is variable, and most estimates come from single institutional studies. The purpose of the present study was to determine the incidence of hypothyroidism at the population level, and to evaluate predictive factors for hypothyroidism after hemithyroidectomy.
methodsThis retrospective study identified euthyroid patients who underwent hemithyroidectomy between 2000 and 2010 for benign disease in Kaiser Permanente Southern California regional hospitals. The incidence of hypothyroidism [thyroid stimulating hormone (TSH) levels >4 μIU/ml] was analyzed. The independent effect of age-quartile, gender, race, thyroiditis, and preoperative TSH level on the development of hypothyroidism was evaluated.
resultsOf 1,240 euthyroid patients identified, 417 (34 %) developed hypothyroidism, and 314 (25 % of total group) needed levothyroxine. Hypothyroidism was more common in age-quartile 2 (32 %), age-quartile 3 (37 %), and age-quartile 4 (42 %) than in age-quartile 1 (25 %) [adjusted odds ratio (OR) = 1.87; 95 % confidence interval (CI) 1.27-2.76, p = 0.002; age-quartile 4 compared to age-quartile 1]. Hypothyroidism was more frequent with increasing preoperative TSH levels 36, 72, and 92 % in patients with TSH levels of 1.0-2, 2.01-3, and 3.01-4 μIU/ml, respectively, compared to 17 % in those with TSH levels <1 μIU/ml [adjusted OR = 45.1; 95 % CI 13.5-151, p < 0.0001; 3.01-4 μIU/ml compared to <1 μIU/ml]. Thyroiditis was also an independent predictor of hypothyroidism.
conclusionsAbout one third of euthyroid patients who undergo hemithyroidectomy develop hypothyroidism. The most significant predictor is the preoperative TSH level, with an approximate doubling of risk for each 1 unit of TSH increase over 1 μIU/ml. Our categorical scale is simple and allows for easy recall when counseling patients preoperatively.
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