Evidence map›Paper›PMID 23982743›Full record

ArticleTransgenic research2014

Osmotin-expressing transgenic tea plants have improved stress tolerance and are of higher quality.

Amita Bhattacharya, Uksha Saini, Robin Joshi, Devinder Kaur, Awadhesh Kumar Pal, Nitish Kumar, Ashu Gulati, Prashant Mohanpuria, Sudesh Kumar Yadav, Sanjay Kumar and 1 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Transgenic research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05937802 (Exploratory Trial of Forza™️, a Novel Nutraceutical From Actinidia Deliciosa Plants Bioengineered to Bio-encapsulate the Osmotin Plant Protein as Adjuvant for the Treatment of Progressive Multiple Sclerosis), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05937802 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Exploratory Trial of Forza™️, a Novel Nutraceutical From Actinidia Deliciosa Plants Bioengineered to Bio-encapsulate the Osmotin Plant Protein as Adjuvant for the Treatment of Progressive Multiple Sclerosis

TypeinterventionalSponsorOspedale Policlinico San MartinoRan2023 to 2025Enrolled50ConditionsProgressive Multiple SclerosisArmsOsmotin
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. ArabidopsisInternational journal of molecular sciences · 2021
    Article
  8. Article
  9. Review
  10. Differential gene expression of salt-stressedJournal, genetic engineering & biotechnology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Amita BhattacharyaCSIR- Institute of Himalayan Bioresource Technology, Council of Scientific and Industrial Research (CSIR), Palampur, 176061, Himachal Pradesh, India, amitabhatta@ihbt.res.in.
Uksha Saini
Robin Joshi
Devinder Kaur
Awadhesh Kumar Pal
Nitish Kumar
Ashu Gulati
Prashant Mohanpuria
Sudesh Kumar Yadav
Sanjay Kumar
Paramvir Singh Ahuja
Institute of Himalayan Bioresource Technology · INCouncil of Scientific and Industrial Research · INBihar Agricultural University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drought is a major stress that affects the yield and quality of tea, a widely consumed beverage crop grown in more than 20 countries of the world. Therefore, osmotin gene-expressing transgenic tea plants produced using earlier optimized conditions were evaluated for their tolerance of drought stress and their quality. Improved tolerance of polyethylene glycol-induced water stress and faster recovery from stress were evident in transgenic lines compared with the normal phenotype. Significant improvements in growth under in-vitro conditions were also observed. Besides enhanced reactive oxygen species-scavenging enzyme activity, the transgenic lines contained significantly higher levels of flavan-3-ols and caffeine, key compounds that govern quality and commercial yield of the beverage. The selected transgenic lines have the potential to meet the demands of the tea industry for stress-tolerant plants with higher yield and quality. These traits of the transgenic lines can be effectively maintained for generations because tea is commercially cultivated through vegetative propagation only.

Indexed as

DroughtsAdaptation, BiologicalAnalysis of VarianceCaffeineCamellia sinensisChromatography, High Pressure LiquidFlavonoidsFree Radical ScavengersPlant LeavesPlant ProteinsPlants, Genetically ModifiedPolyethylene GlycolsReverse Transcriptase Polymerase Chain ReactionStress, PhysiologicalCaffeineflavan-3-olFlavonoidsFree Radical Scavengersosmotin protein, Nicotiana tabacumPlant ProteinsPolyethylene Glycols

Identifiers

PMID23982743
OpenAlexW2053597053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.