ArticleEndocrine2014
Serum levels of 25-hydroxyvitamin D are associated with cognitive impairment in type 2 diabetic adults.
Article in Endocrine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Vitamin D Supplementation and Cognition in People with Type 2 Diabetes: A Randomized Control Trial.Journal of diabetes research · 2019Trial
- [Effect of vitamin D3 on mild cognitive impairment in type 2 diabetic mice and its possible mechanism].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Potential role of 25(OH)D insufficiency in the dysfunction of glycolipid metabolism and cognitive impairment in patients with T2DM.Frontiers in endocrinology · 2022Article
- Article
- Association of serum 25-hydroxyvitamin D concentrations with risk of dementia among individuals with type 2 diabetes: A cohort study in the UK Biobank.PLoS medicine · 2022Article
- Vitamin DFood science & nutrition · 2021Article
- Attenuated serum 25-hydroxyvitamin D and vitamin D binding protein associated with cognitive impairment in patients with type 2 diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Low vitamin D levels are associated with cognitive impairment in patients with Hashimoto thyroiditis.BMC endocrine disorders · 2018Article
- Plasma soluble CD36, carotid intima-media thickness and cognitive function in patients with type 2 diabetes.Archives of medical science : AMS · 2017Article
- The impact of vitamin D deficiency on patients undergoing kidney transplantation: focus on cardiovascular, metabolic, and endocrine outcomes.Endocrine · 2015Review
- The Role of Vitamin D in Diabetes and Cardiovascular Disease: An Updated Review of the Literature.Disease markers · 2015Review
- IMPACT OF VITAMIN D DEFICIENCY ON COGNITIVE FUNCTIONS IN TYPE 2 DIABETIC PATIENTS.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypovitaminosis D is highly prevalent in type 2 diabetes. The aim of this study is to determine the serum levels of 25-hydroxyvitamin D [25(OH)D] in type 2 diabetic patients with and without mild cognitive impairment (MCI), and examine the relationship of 25(OH)D and MCI with other clinical factors. One hundred and sixty-five diabetic patients were enrolled in this study. Among whom, 95 patients were considered as MCI [Montreal Cognitive Assessment score (MoCA) < 26] and the other 70 as no MCI (MoCA ≥ 26). Subjects were assessed clinically. Diabetic patients with MCI had a longer duration of DM, fewer years of education, elevated fasting blood glucose (FBG), resistant index (RI) of carotid, and lower levels of 25(OH)D {[17.35 (13.02-25.92) vs 28.00 (19.67-34.30)] ng/ml, P < 0.001}. The MoCA score was positively correlated with log10[25(OH)D], education year, and inversely correlated with duration of DM, history of hypertension, intima-media thickness (IMT), FBG, max-RI, and min-RI. Log10[25(OH)D] was positively correlated with MoCA score, and inversely correlated with IMT, in multivariate regression analysis adjusted for age, sex, and education year, 25(OH)D (β = 0.210, P = 0.003), history of hypertension (β = -0.191, P = 0.007), IMT (β = -0.194, P = 0.007), and FBG (β = -0.157, P = 0.026) independently predicted MoCA score. In conclusion, our results suggest that levels of serum 25(OH)D are inversely associated with the cognitive impairment in diabetic patients. Vitamin D may be a potential protective factor for cognitive impairment in patients with type 2 diabetes.
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