Ketamine for treatment-resistant depression: ready or not for clinical use?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. A randomized controlled trial of intranasal ketamine in major depressive disorder.Biological psychiatry · 2014
   Trial
2. Ketamine: stimulating antidepressant treatment?BJPsych open · 2016
   Article
3. Evidence that Subanesthetic Doses of Ketamine Cause Sustained Disruptions of NMDA and AMPA-Mediated Frontoparietal Connectivity in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
   Article
4. Antidepressant actions of ketamine: from molecular mechanisms to clinical practice.Current opinion in neurobiology · 2015
   Review
5. Glia in the cytokine-mediated onset of depression: fine tuning the immune response.Frontiers in cellular neuroscience · 2015
   Review
6. Ketamine, Transcranial Magnetic Stimulation, and Depression Specific Yoga and Mindfulness Based Cognitive Therapy in Management of Treatment Resistant Depression: Review and Some Data on Efficacy.Depression research and treatment · 2015
   Review
7. The role of ketamine in treatment-resistant depression: a systematic review.Current neuropharmacology · 2014
   Article
8. The R-Stereoisomer of Ketamine as an Alternative for Ketamine for Treatment-resistant Major Depression.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2014
   Article

Corrections and comments

• Comment on
  Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.2013

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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