Evidence map›Paper›PMID 23981598›Full record

ReviewTopics in antiviral medicine

Treatment as prevention: toward an AIDS-free generation.

Julio S G Montaner

Abstract readReview
In one paragraph

Review in Topics in antiviral medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
  2. Article
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  5. Article
  6. Review
  7. Using HIV Sequence and Epidemiologic Data to Assess the Effect of Self-referral Testing for Acute HIV Infection on Incident Diagnoses in San Diego, California.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Julio S G MontanerUniversity of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In British Columbia, Canada, intensive efforts have been made to implement and maintain a treatment-as-prevention strategy among the HIV-infected population. Acceleration of antiretroviral therapy coverage has resulted in a substantial increase in the median CD4+ cell count at which treatment is initiated and a dramatic decline in community plasma HIV RNA levels. This has resulted in a reduction in diagnoses of new cases of HIV infection, including among injection drug users. Proportions of individuals with viral suppression have steadily increased and the expansion of antiretroviral therapy coverage has not been associated with increased levels of HIV resistance. Further, adoption of routine HIV testing in acute care settings has been very well accepted and has captured new cases at a rate of 5 per 1000 tests outside of high-risk populations, offering an additional strategy for identifying and linking at least some individuals with undiagnosed HIV infection to care. Deriving optimal individual and social health outcomes in HIV infection requires improvement in every element of the cascade of care. This article summarizes a presentation by Julio S. G. Montaner, MD, at the IAS-USA continuing education program held in San Francisco, California, in March 2013.

Indexed as

Anti-Retroviral AgentsBritish ColumbiaCD4 Lymphocyte CountCommunicable Disease ControlDisease EradicationHIV InfectionsHumansRNA, ViralAnti-Retroviral AgentsRNA, Viral

Identifiers

PMID23981598
PMCPMC6148874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.