ArticleNeurotoxicology and teratology
Effects of prenatal cocaine exposure on child behavior and growth at 10 years of age.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Prenatal stress and externalizing behaviors in childhood and adolescence: A systematic review and meta-analysis.Psychological bulletin · 2024Pooled it
- Research Review: Developmental origins of depression - a systematic review and meta-analysis.Journal of child psychology and psychiatry, and allied disciplines · 2021Pooled it
- Decoding neurodevelopment risks of exposures to intoxication, infection, and trauma during pregnancy.Pregnancy (Hoboken, N.J.) · 2026Review
- Melanin-Concentrating Hormone (MCH): Role in Mediating Reward-Motivated and Emotional Behavior and the Behavioral Disturbances Produced by Repeated Exposure to Reward Substances.International journal of molecular sciences · 2025Review
- Prenatal cocaine exposure and self-reported behavioral adjustments from ages 12 to 21: environmental pathways.Psychological medicine · 2024Article
- Adverse childhood experiences are associated with illicit drug use among pregnant women with middle to high socioeconomic status: findings from the All Our Families Cohort.BMC pregnancy and childbirth · 2021Article
- Associations of Maternal Prenatal Drug Abuse With Measures of Newborn Brain Structure, Tissue Organization, and Metabolite Concentrations.JAMA pediatrics · 2020Article
- Prenatal cocaine exposure: Direct and indirect associations with 21-year-old offspring substance use and behavior problems.Drug and alcohol dependence · 2019Article
- Substance use in pregnancy: The medical challenge.Obstetric medicine · 2018Review
- Substance Use in the Perinatal Period.Current psychiatry reports · 2015Review
- Predictors of Childhood Depressed Mood: A Two-Generational Study.Journal of child and family studies · 2015Article
- Developmental consequences of fetal exposure to drugs: what we know and what we still must learn.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015Review
- Prenatal cocaine exposure and age of sexual initiation: direct and indirect effects.Drug and alcohol dependence · 2014Article
- Self-reported adolescent behavioral adjustment: effects of prenatal cocaine exposure.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2014Article
- Prenatal cocaine exposure, early cannabis use, and risky sexual behavior at age 25.Neurotoxicology and teratologyArticle
- Effects of prenatal cocaine exposure on adolescent development.Neurotoxicology and teratologyArticle
- Prenatal drug exposure and executive function in early adolescence.Neurotoxicology and teratologyArticle
- Effects of prenatal cocaine exposure on pubertal development.Neurotoxicology and teratologyArticle
- Pathways from prenatal cocaine exposure to adult substance use and behavior.Neurotoxicology and teratologyArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
We examined physical growth and behavioral outcomes in 226 10-year-old children who were participants in a longitudinal study of prenatal cocaine exposure (PCE), while controlling for other factors that affect development. During the first trimester, 42% of the women used cocaine, with use declining across pregnancy. At the 10-year follow-up, the caregivers were 37years old, had 12.8years of education, and 50% were African American. First trimester cocaine exposure predicted decreased weight, height, and head circumference at 10years. First trimester cocaine use also predicted maternal ratings of less sociability on the EAS Temperament Survey and more withdrawn behavior problems on the Child Behavior Checklist, more anxious/depressed behaviors on the Teacher Report Form, and more self-reported depressive symptoms on the Children's Depression Inventory. In addition, exposure to violence mediated the effect of PCE on child and teacher reports of depressive symptoms, but not of maternal reports of sociability and withdrawn behaviors. These behaviors may be precursors of later psychiatric problems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.