ArticleProceedings of the National Academy of Sciences of the United States of America2013
Impact of a single base pair substitution on the charge transfer rate along short DNA hairpins.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- High Electronic Conductance through Double-Helix DNA Molecules with Fullerene Anchoring Groups.The journal of physical chemistry. A · 2017Article
- Deep-hole transfer leads to ultrafast charge migration in DNA hairpins.Nature chemistry · 2016Article
- Redox Signaling through DNA.Israel journal of chemistry · 2016Article
- Engineering nanometre-scale coherence in soft matter.Nature chemistry · 2016Article
- Length-independent transport rates in biomolecules by quantum mechanical unfurling.Chemical science · 2016Article
- Article
- Quantitative prediction of charge mobilities of π-stacked systems by first-principles simulation.Nature protocols · 2015Article
- Charge separation and charge delocalization identified in long-living states of photoexcited DNA.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Numerical studies of hole migration along short DNA hairpins were performed with a particular emphasis on the variations of the rate and quantum yield of the charge separation process with the location of a single guanine:cytosine (G:C) base pair. Our calculations show that the hole arrival rate increases as the position of the guanine:cytosine base pair shifts from the beginning to the end of the sequence. Although these results are in agreement with recent experimental findings, the mechanism governing the charge migration along these sequences is revisited here. Instead of the phenomenological two-step hopping mechanism via the guanine base, the charge propagation occurs through a delocalization of the hole density along the base pair stack. Furthermore, the variations of the charge transfer with the position of the guanine base are explained by the impact of the base pair substitutions on the delocalized conduction channels.
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Registered trials
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