Evidence map›Paper›PMID 23980135›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2014

The prevalence of sarcopenia in patients with respiratory failure classified as normally nourished using computed tomography and subjective global assessment.

Patricia M Sheean, Sarah J Peterson, Sandra Gomez Perez, Karen L Troy, Ankur Patel, Joy S Sclamberg, Folabomi C Ajanaku, Carol A Braunschweig

Abstract read
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.

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  12. Aging versus youth: Endocrine aspects of vulnerability for COVID-19.Reviews in endocrine & metabolic disorders · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Patricia M SheeanInstitute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA psheea1@uic.edu.
Sarah J PetersonDepartment of Food and Nutrition, Rush University Medical Center, Chicago, IL, USA.
Sandra Gomez PerezInstitute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA.
Karen L TroyDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA.
Ankur PatelDiagnostic Radiology & Nuclear Medicine Department, Rush University Medical Center, Chicago, IL, USA.
Joy S SclambergRush University Medical Center, Chicago, IL, USA.
Folabomi C AjanakuHoward University College of Medicine, Washington, DC, USA.
Carol A BraunschweigInstitute for Health Research and Policy, University of Illinois at Chicago, Chicago, IL, USA.
University of Illinois Chicago · USRush University Medical Center · USHoward University · US

Funding

UIC CANCER PREVENTION &CONTROL RESEARCH TRAINING GRANTR25CA057699 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FITZGIBBON, MARIAN L. · 1992 to 2017
$8.2M
Intensive Nutrition in ARDS: A Clinical Trial (INTACT)R01HL093142 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BRAUNSCHWEIG, CAROL L · 2008 to 2012
$2.2M
NCI NIH HHS R25 CA057699NCI NIH HHS R25CA057699-18NHLBI NIH HHS R01 HL093142NHLBI NIH HHS R01 HL093142-02
6 · The paper itself

Abstract

backgroundDeclines in nutrition status and adverse body composition changes frequently occur in the critically ill. The objective of this cross-sectional study was to examine the prevalence of sarcopenia and its occurrence in patients classified as normal nourished using subjective global assessment (SGA).

methodsExploiting diagnostic CT images, skeletal muscle mass at the L3 region was quantified and used to determine sarcopenia and its association with normal nutrition status in 56 patients with respiratory failure. Sarcopenia was defined as an L3 skeletal muscle index of ≤38.5 cm(2)/m(2) for women and ≤52.4 cm(2)/m(2) for men. CT imaging and SGA classifications completed within 14, 10 and 7 days of each other were analyzed to assess sarcopenia and the influence of time between scans on misclassification (ie, normal nourished and sarcopenic). Descriptive statistics were conducted.

resultsThe average patient was 59.2 (± 15.6) years old, admitted with sepsis/infection, an APACHE II score of 26 (± 8.0), and BMI of 28.3 (± 5.8). Sarcopenia and sarcopenic obesity were prevalent in a minimum of 56% and 24% of patients, respectively, depending on the number of days between CT imaging and SGA assessment. Misclassified individuals were predominantly male, minority and overweight or obese. Controlling for age, no significant differences were noted for patients classified as normal nourished vs malnourished by SGA for lumbar muscle cross-sectional, whole-body lean mass, or skeletal muscle index.

conclusionsSarcopenia is highly prevalent among patients with respiratory failure requiring mechanical ventilation (MV) and not readily detected in patients classified as normal nourished using SGA.

Indexed as

Body CompositionMuscle, SkeletalNutritional StatusAdultAgedBody Mass IndexCritical IllnessCross-Sectional StudiesFemaleHumansMaleMiddle AgedMinority GroupsNutrition AssessmentObesityOverweightcomputed tomographymalnutritionsarcopeniasarcopenic obesitysubjective global assessment

Identifiers

PMID23980135
PMCPMC3935982
OpenAlexW1968446222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.