Evidence map›Paper›PMID 23980011›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2013

The dynamics of DNA damage repair and transcription.

Niraj M Shanbhag, Roger A Greenberg

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. FKBP25 participates in DNA double-strand break repair.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2020
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Niraj M ShanbhagDepartment of Cancer Biology, Abramson Family Cancer Research Institute, Basser Research Center for BRCA1/2, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Roger A Greenberg

Funding

The RAP80-BRCC36 Deubiquitinating Complex in DNA RepairR01CA138835 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Roger A Greenberg · 2010 to 2026
$5.2M
Roles of Chromatin Modification in BRCA1 Dependent DNA RepairR01CA174904 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Roger A Greenberg · 2013 to 2026
$4.8M
DNA Double Strand Break Chromatin Alterations and Genome IntegrityR01GM101149 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GREENBERG, ROGER A · 2013 to 2025
$4.0M
NCI NIH HHS R01 CA138835NCI NIH HHS R01 CA174904NIGMS NIH HHS R01 GM101149
6 · The paper itself

Abstract

Recent advances have led to several systems to study transcription from defined loci in living cells. It has now become possible to address long-standing questions regarding the interplay between the processes of DNA damage repair and transcription-two disparate processes that can occur on the same stretch of chromatin and which both lead to extensive chromatin change. Here we describe the development of a system to create enzymatically induced DNA double-strand breaks (DSBs) at a site of inducible transcription and methods to study the interplay between these processes.

Indexed as

DNA Breaks, Double-StrandedAnimalsAnti-Bacterial AgentsAntineoplastic AgentsCell LineChromatinChromatin Assembly and DisassemblyDeoxyribonucleases, Type II Site-SpecificDNA RepairDoxycyclineHumansLac OperonLasersMicroscopy, FluorescenceTamoxifenTranscription, GeneticafimoxifeneAnti-Bacterial AgentsAntineoplastic AgentsChromatinDeoxyribonucleases, Type II Site-SpecificDoxycyclineendodeoxyribonuclease FokITamoxifen

Identifiers

PMID23980011
PMCPMC3827964

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.