ArticleG3 (Bethesda, Md.)2013
Genetic architecture of parallel pelvic reduction in ninespine sticklebacks.
Article in G3 (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Post-translational modification networks in tumor radiosensitivity: mechanistic insights and therapeutic opportunities.Journal of translational medicine · 2026Review
- Same trait, different genes: pelvic spine loss in three brook stickleback populations in Alberta, Canada.Evolution letters · 2025Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Whole-genome Comparisons Identify Repeated Regulatory Changes Underlying Convergent Appendage Evolution in Diverse Fish Lineages.Molecular biology and evolution · 2023Article
- Pelvic spine reduction affects diet but not gill raker morphology in two polymorphic brook stickleback (Ecology and evolution · 2023Article
- Prevalent Introgression Underlies Convergent Evolution in the Diversification of Pungitius Sticklebacks.Molecular biology and evolution · 2023Article
- Whole-genome comparisons identify repeated regulatory changes underlying convergent appendage evolution in diverse fish lineages.bioRxiv : the preprint server for biology · 2023Article
- Comparing genome scans among species of the stickleback order reveals three different patterns of genetic diversity.Ecology and evolution · 2022Article
- (Non)Parallel developmental mechanisms in vertebrate appendage reduction and loss.Ecology and evolution · 2021Review
- A High-Quality Assembly of the Nine-Spined Stickleback (Pungitius pungitius) Genome.Genome biology and evolution · 2019Article
- The evolution of sex determination associated with a chromosomal inversion.Nature communications · 2019Article
- Ancient genomic variation underlies repeated ecological adaptation in young stickleback populations.Evolution letters · 2018Article
- Pigeonetics takes flight: Evolution, development, and genetics of intraspecific variation.Developmental biology · 2017Review
- The genetic and molecular architecture of phenotypic diversity in sticklebacks.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Quantitative trait locus analysis of body shape divergence in nine-spined sticklebacks based on high-density SNP-panel.Scientific reports · 2016Article
- Molecular shifts in limb identity underlie development of feathered feet in two domestic avian species.eLife · 2016Article
- Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback.G3 (Bethesda, Md.) · 2015Article
- Construction of Ultradense Linkage Maps with Lep-MAP2: Stickleback F2 Recombinant Crosses as an Example.Genome biology and evolution · 2015Article
- Convergent Evolution of Head Crests in Two Domesticated Columbids Is Associated with Different Missense Mutations in EphB2.Molecular biology and evolution · 2015Article
- Genome-wide linkage disequilibrium in nine-spined stickleback populations.G3 (Bethesda, Md.) · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Teleost fish genomes are known to be evolving faster than those of other vertebrate taxa. Thus, fish are suited to address the extent to which the same vs. different genes are responsible for similar phenotypic changes in rapidly evolving genomes of evolutionary independent lineages. To gain insights into the genetic basis and evolutionary processes behind parallel phenotypic changes within and between species, we identified the genomic regions involved in pelvic reduction in Northern European ninespine sticklebacks (Pungitius pungitius) and compared them to those of North American ninespine and threespine sticklebacks (Gasterosteus aculeatus). To this end, we conducted quantitative trait locus (QTL) mapping using 283 F2 progeny from an interpopulation cross. Phenotypic analyses indicated that pelvic reduction is a recessive trait and is inherited in a simple Mendelian fashion. Significant QTL for pelvic spine and girdle lengths were identified in the region of the Pituitary homeobox transcription factor 1 (Pitx1) gene, also responsible for pelvic reduction in threespine sticklebacks. The fact that no QTL was observed in the region identified in the mapping study of North American ninespine sticklebacks suggests that an alternative QTL for pelvic reduction has emerged in this species within the past 1.6 million years after the split between Northern European and North American populations. In general, our study provides empirical support for the view that alternative genetic mechanisms that lead to similar phenotypes can evolve over short evolutionary time scales.
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