ArticleGenetics2013
Targeted heritable mutation and gene conversion by Cas9-CRISPR in Caenorhabditis elegans.
Article in Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed.
- Genome editing using CRISPR, CAST, and Fanzor systems.Molecules and cells · 2024Review
- Modular safe-harbor transgene insertion for targeted single-copy and extrachromosomal array integration in Caenorhabditis elegans.G3 (Bethesda, Md.) · 2022Article
- Interactions of Caenorhabditis elegans β-tubulins with the microtubule inhibitor and anthelmintic drug albendazole.Genetics · 2022Article
- Visualizing and quantifying molecular and cellular processes in Caenorhabditis elegans using light microscopy.Genetics · 2022Review
- Single nucleotide substitutions effectively block Cas9 and allow for scarless genome editing in Caenorhabditis elegans.Genetics · 2022Article
- Bisection of the X chromosome disrupts the initiation of chromosome silencing during meiosis in Caenorhabditis elegans.Nature communications · 2021Article
- Fast genetic mapping using insertion-deletion polymorphisms in Caenorhabditis elegans.Scientific reports · 2021Article
- Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect.Gene therapy · 2020Article
- Genome editing in the nematodeBiology methods & protocols · 2020Article
- Peel-1 negative selection promotes screening-free CRISPR-Cas9 genome editing in Caenorhabditis elegans.PloS one · 2020Article
- Production of a mutant of large-scale loach Paramisgurnus dabryanus with skin pigmentation loss by genome editing with CRISPR/Cas9 system.Transgenic research · 2019Article
- TheGenetics · 2019Review
- Article
- Strategies for Efficient Genome Editing Using CRISPR-Cas9.Genetics · 2019Article
- CRISPR/Cas9 Methodology for the Generation of Knockout Deletions inG3 (Bethesda, Md.) · 2019Article
- An Efficient Genome Editing Strategy To Generate Putative Null Mutants inG3 (Bethesda, Md.) · 2018Article
- Targeted Chromosomal Rearrangements via Combinatorial Use of CRISPR/Cas9 and Cre/G3 (Bethesda, Md.) · 2018Article
- PRP-19, a conserved pre-mRNA processing factor and E3 ubiquitin ligase, inhibits the nuclear accumulation of GLP-1/Notch intracellular domain.Biology open · 2018Article
- Reliable CRISPR/Cas9 Genome Engineering inG3 (Bethesda, Md.) · 2017Article
- The Bright Fluorescent Protein mNeonGreen Facilitates Protein Expression AnalysisG3 (Bethesda, Md.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
We have achieved targeted heritable genome modification in Caenorhabditis elegans by injecting mRNA of the nuclease Cas9 and Cas9 guide RNAs. This system rapidly creates precise genomic changes, including knockouts and transgene-instructed gene conversion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.