ArticleArchives of microbiology2013
Genes from the exo-xis region of λ and Shiga toxin-converting bacteriophages influence lysogenization and prophage induction.
Article in Archives of microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Factors Governing the Cross-Species Virulence of Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2026Article
- Therapeutic potential of Shigella phage SSG23 against Shigella sonnei biofilms and in BALB/c mice.Npj viruses · 2025Article
- Utilizing the effectiveness of phage cocktail to combat Shigella and Salmonella infections and their polymicrobial biofilm control activity.BMC microbiology · 2025Article
- The NMR structure of the Orf63 lytic developmental protein from lambda bacteriophage.Scientific reports · 2024Article
- Complex effects of the exo-xis region of the Shiga toxin-converting bacteriophage Φ24Journal of applied genetics · 2024Article
- Evaluation of phage-antibiotic combinations in the treatment of extended-spectrum β-lactamase-producingHeliyon · 2023Article
- Article
- Isolation and Characterization of Chi-like Salmonella Bacteriophages Infecting Two Salmonella enterica Serovars, Typhimurium and EnteritidisPathogens (Basel, Switzerland) · 2022Article
- Article
- Isolation, characterization, and application of a novel polyvalent lytic phage STWB21 against typhoidal and nontyphoidalFrontiers in microbiology · 2022Article
- Insights into the genome architecture and evolution of Shiga toxin encoding bacteriophages of Escherichia coli.BMC genomics · 2021Article
- Prophage Activation in the Intestine: Insights Into Functions and Possible Applications.Frontiers in microbiology · 2021Review
- Characterization of the Bacteriophage vB_EfaS-271 InfectingInternational journal of molecular sciences · 2020Article
- Ea22 Proteins from Lambda and Shiga Toxin-Producing Bacteriophages Balance Structural Diversity with Functional Similarity.ACS omega · 2020Article
- The ea22 gene of lambdoid phages: preserved prolysogenic function despite of high sequence diversity.Virus genes · 2020Article
- Characterization of a bacteriophage, vB_Eco4M-7, that effectively infects many Escherichia coli O157 strains.Scientific reports · 2020Article
- Roles ofViruses · 2018Article
- Characterization of Bacteriophage vB-EcoS-95, Isolated From Urban Sewage and Revealing Extremely Rapid Lytic Development.Frontiers in microbiology · 2018Article
- Bad Phages in Good Bacteria: Role of the MysteriousFrontiers in microbiology · 2017Article
- The Role of the Exo-Xis Region in Oxidative Stress-Mediated Induction of Shiga Toxin-Converting Prophages.Oxidative medicine and cellular longevity · 2016Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The exo-xis region, present in genomes of lambdoid bacteriophages, contains highly conserved genes of largely unknown functions. In this report, using bacteriophage λ and Shiga toxin-converting bacteriophage ϕ24Β, we demonstrate that the presence of this region on a multicopy plasmid results in impaired lysogenization of Escherichia coli and delayed, while more effective, induction of prophages following stimulation by various agents (mitomycin C, hydrogen peroxide, UV irradiation). Spontaneous induction of λ and ϕ24Β prophages was also more efficient in bacteria carrying additional copies of the corresponding exo-xis region on plasmids. No significant effects of an increased copy number of genes located between exo and xis on both efficiency of adsorption on the host cells and lytic development inside the host cell of these bacteriophages were found. We conclude that genes from the exo-xis region of lambdoid bacteriophages participate in the regulation of lysogenization and prophage maintenance.
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