ArticleJournal of biomedical optics2014
Hybrid photomultiplier tube and photodiode parallel detection array for wideband optical spectroscopy of the breast guided by magnetic resonance imaging.
Article in Journal of biomedical optics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Development of digital breast tomosynthesis and diffuse optical tomography fusion imaging for breast cancer detection.Scientific reports · 2020Trial
- Deep Learning Enables Fast and Accurate Quantification of MRI-Guided Near-Infrared Spectral Tomography for Breast Cancer Diagnosis.IEEE transactions on medical imaging · 2025Article
- Widefield ultra-high-density optical breast tomography system supplementing x-ray mammography.Scientific reports · 2025Article
- In vivo optimization of the experimental conditions for the non-invasive optical assessment of breast density.Scientific reports · 2024Article
- Fabrication of a Reflective Optical Imaging Device for Early Detection of Breast Cancer.Bioengineering (Basel, Switzerland) · 2023Article
- Review of recent advances in frequency-domain near-infrared spectroscopy technologies [Invited].Biomedical optics express · 2023Review
- Deep-learning based image reconstruction for MRI-guided near-infrared spectral tomography.Optica · 2022Article
- A review of optical breast imaging: Multi-modality systems for breast cancer diagnosis.European journal of radiology · 2020Review
- Hybrid time-domain and continuous-wave diffuse optical tomography instrument with concurrent, clinical magnetic resonance imaging for breast cancer imaging.Journal of biomedical optics · 2019Article
- Compact ultrasound-guided diffuse optical tomography system for breast cancer imaging.Journal of biomedical optics · 2018Article
- Direct Regularization From Co-Registered Contrast MRI Improves Image Quality of MRI-Guided Near-Infrared Spectral Tomography of Breast Lesions.IEEE transactions on medical imaging · 2018Article
- Breast density quantification using structured-light-based diffuse optical tomography simulations.Applied optics · 2017Article
- Collagen quantification in breast tissue using a 12-wavelength near infrared spectral tomography (NIRST) system.Biomedical optics express · 2017Article
- Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis.Journal of biomedical optics · 2017Article
- Portable, parallel 9-wavelength near-infrared spectral tomography (NIRST) system for efficient characterization of breast cancer within the clinical oncology infusion suite.Biomedical optics express · 2016Article
- Experimental validation of a high-resolution diffuse optical imaging modality: photomagnetic imaging.Journal of biomedical optics · 2016Article
- Frequency domain near-infrared multiwavelength imager design using high-speed, direct analog-to-digital conversion.Journal of biomedical optics · 2016Article
- MR-Guided Near-Infrared Spectral Tomography Increases Diagnostic Performance of Breast MRI.Clinical cancer research : an official journal of the American Association for Cancer Research · 2015Article
- Direct regularization from co-registered anatomical images for MRI-guided near-infrared spectral tomographic image reconstruction.Biomedical optics express · 2015Article
- Optimization of image reconstruction for magnetic resonance imaging-guided near-infrared diffuse optical spectroscopy in breast.Journal of biomedical optics · 2015Article
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5 authors.
Funding
Abstract
A new optical parallel detection system of hybrid frequency and continuous-wave domains was developed to improve the data quality and accuracy in recovery of all breast optical properties. This new system was deployed in a previously existing system for magnetic resonance imaging (MRI)-guided spectroscopy, and allows incorporation of additional near-infrared wavelengths beyond 850 nm, with interlaced channels of photomultiplier tubes (PMTs) and silicon photodiodes (PDs). The acquisition time for obtaining frequency-domain data at six wavelengths (660, 735, 785, 808, 826, and 849 nm) and continuous-wave data at three wavelengths (903, 912, and 948 nm) is 12 min. The dynamic ranges of the detected signal are 105 and 106 for PMT and PD detectors, respectively. Compared to the previous detection system, the SNR ratio of frequency-domain detection was improved by nearly 103 through the addition of an RF amplifier and the utilization of programmable gain. The current system is being utilized in a clinical trial imaging suspected breast cancer tumors as detected by contrast MRI scans.
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