Evidence map›Paper›PMID 23979272›Full record

Trial reportAnnals of surgery2013

Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties.

Thomas N Robinson, Daniel S Wu, Angela Sauaia, Christina L Dunn, Jennifer E Stevens-Lapsley, Marc Moss, Greg V Stiegmann, Csaba Gajdos, Joseph C Cleveland, Sharon K Inouye

Abstract readClinical Trial
In one paragraph

Trial report in Annals of surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  5. Timed Stair-Climbing as a Surrogate Marker for Sarcopenia Measurements in Predicting Surgical Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Thomas N Robinson*Department of Surgery †School of Public Health ‡Department of Physical Medicine and Rehabilitation Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO §Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School and Institute for Aging Research, Hebrew SeniorLife, Boston, MA ¶Department of Surgery, Denver Veteran Affairs Medical Center, Denver, CO.
Daniel S Wu
Angela Sauaia
Christina L Dunn
Jennifer E Stevens-Lapsley
Marc Moss
Greg V Stiegmann
Csaba Gajdos
Joseph C Cleveland
Sharon K Inouye

Funding

The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2010 to 2022
$26.7M
Patient Oriented Research Program in ALI/ARFK24HL089223 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MOSS, MARC · 2007 to 2016
$1.4M
A Placebo Controlled Trial of L-Tryptophan in Post-Operative DeliriumK23AG034632 · NIA · UNIVERSITY OF COLORADO DENVER · PI ROBINSON, THOMAS NICHOLS · 2010 to 2014
$764k
NHLBI NIH HHS K24 HL089223NHLBI NIH HHS NIH K24-HL-089223NIA NIH HHS K23 AG034632NIA NIH HHS NIA K23AG034632NIA NIH HHS NIH P01AG031720NIA NIH HHS P01 AG031720
6 · The paper itself

Abstract

objectiveThe purpose of this study was to determine the relationship between the Timed Up and Go test and postoperative morbidity and 1-year mortality, and to compare the Timed Up and Go to the standard-of-care surgical risk calculators for prediction of postoperative complications.

methodsIn this prospective cohort study, patients 65 years and older undergoing elective colorectal and cardiac operations with a minimum of 1-year follow-up were included. The Timed Up and Go test was performed preoperatively. This timed test starts with the subject standing from a chair, walking 10 feet, returning to the chair, and ends after the subject sits. Timed Up and Go results were grouped as fast ≤ 10 seconds, intermediate = 11-14 seconds, and slow ≥ 15 seconds. Receiver operating characteristic curves were used to compare the 3 Timed Up and Go groups to current standard-of-care surgical risk calculators at forecasting postoperative complications.

resultsThis study included 272 subjects (mean age of 74 ± 6 years). Slower Timed Up and Go was associated with increased postoperative complications after colorectal (fast 13%, intermediate 29%, and slow 77%; P < 0.001) and cardiac (fast 11%, intermediate 26%, and slow 52%; P < 0.001) operations. Slower Timed Up and Go was associated with increased 1-year mortality following both colorectal (fast 3%, intermediate 10%, and slow 31%; P = 0.006) and cardiac (fast 2%, intermediate 3%, and slow 12%; P = 0.039) operations. Receiver operating characteristic area under curve of the Timed Up and Go and the risk calculators for the colorectal group was 0.775 (95% CI: 0.670-0.880) and 0.554 (95% CI: 0.499-0.609), and for the cardiac group was 0.684 (95% CI: 0.603-0.766) and 0.552 (95% CI: 0.477-0.626).

conclusionsSlower Timed Up and Go forecasted increased postoperative complications and 1-year mortality across surgical specialties. Regardless of operation performed, the Timed Up and Go compared favorably to the more complex risk calculators at forecasting postoperative complications.

Indexed as

Decision Support TechniquesPreoperative CareAgedAged, 80 and overCardiac Surgical ProceduresDigestive System Surgical ProceduresElective Surgical ProceduresFemaleFollow-Up StudiesHumansKaplan-Meier EstimateMalePostoperative ComplicationsPrognosisProspective StudiesRisk Assessment

Identifiers

PMID23979272
PMCPMC3771691

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.