ArticleJournal of radiation research2014
Adaptive response in human blood lymphocytes exposed to non-ionizing radiofrequency fields: resistance to ionizing radiation-induced damage.
Article in Journal of radiation research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- A scoping review and evidence map of radiofrequency field exposure and genotoxicity: assessingFrontiers in public health · 2025Article
- Assessment of Inflammation in 3D Reconstructed Human Skin Exposed to Combined Exposure to Ultraviolet and Wi-Fi Radiation.International journal of molecular sciences · 2023Article
- Differential Radiomodulating Action ofAntioxidants (Basel, Switzerland) · 2022Article
- Inhibition of Autophagy Negates Radiofrequency-Induced Adaptive Response in SH-SY5Y Neuroblastoma Cells.International journal of molecular sciences · 2022Article
- Wearable Antennas for Sensor Networks and IoT Applications: Evaluation of SAR and Biological Effects.Sensors (Basel, Switzerland) · 2022Article
- Evaluation of Inflammation by Cytokine Production Following Combined Exposure to Ultraviolet and Radiofrequency Radiation of Mobile Phones on 3D Reconstructed Human Skin In Vitro.International journal of environmental research and public health · 2020Article
- Two decades (1998-2018) of research Progress on Hormesis: advancing biological understanding and enabling novel applications.Journal of cell communication and signaling · 2019Article
- Treatment with 3-Aminobenzamide Negates the Radiofrequency-Induced Adaptive Response in Two Cell Models.International journal of environmental research and public health · 2019Article
- Protective effect of 1950 MHz electromagnetic field in human neuroblastoma cells challenged with menadione.Scientific reports · 2018Article
- Article
- Exposure to Global System for Mobile Communication 900 MHz Cellular Phone Radiofrequency Alters Growth, Proliferation and Morphology of Michigan Cancer Foundation-7 Cells and Mesenchymal Stem Cells.International journal of preventive medicine · 2018Article
- Effects of low-dose radiation on adaptive response in colon cancer stem cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2017Article
- Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells.International journal of environmental research and public health · 2017Article
- Quality Matters: Systematic Analysis of Endpoints Related to "Cellular Life" in Vitro Data of Radiofrequency Electromagnetic Field Exposure.International journal of environmental research and public health · 2016Review
- Ionizing radiation-induced adaptive response in fibroblasts under both monolayer and 3-dimensional conditions.PloS one · 2015Article
- Mobile phones, non-ionizing radiofrequency fields and brain cancer: is there an adaptive response?Dose-response : a publication of International Hormesis Society · 2014Article
- Adaptive response in animals exposed to non-ionizing radiofrequency fields: some underlying mechanisms.International journal of environmental research and public health · 2014Review
- Searching for the perfect wave: the effect of radiofrequency electromagnetic fields on cells.International journal of molecular sciences · 2014Review
- Looking at the other side of the coin: the search for possible biopositive cognitive effects of the exposure to 900 MHz GSM mobile phone radiofrequency radiation.Journal of environmental health science & engineering · 2014Review
- Repeated 0.2-Gy γ-Ray Irradiation Attenuates the Inflammatory Process and Endotoxin Damage Induced by Lipopolysaccharides.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this preliminary investigation was to assess whether human peripheral blood lymphocytes which have been pre-exposed to non-ionizing radiofrequency fields exhibit an adaptive response (AR) by resisting the induction of genetic damage from subsequent exposure to ionizing radiation. Peripheral blood lymphocytes from four healthy donors were stimulated with phytohemagglutinin for 24 h and then exposed for 20 h to 1950 MHz radiofrequency fields (RF, adaptive dose, AD) at an average specific absorption rate of 0.3 W/kg. At 48 h, the cells were subjected to a challenge dose (CD) of 1.0 or 1.5 Gy X-irradiation (XR, challenge dose, CD). After a 72 h total culture period, cells were collected to examine the incidence of micronuclei (MN). There was a significant decrease in the number of MN in lymphocytes exposed to RF + XR (AD + CD) as compared with those subjected to XR alone (CD). These observations thus suggested a RF-induced AR and induction of resistance to subsequent damage from XR. There was variability between the donors in RF-induced AR. The data reported in our earlier investigations also indicated a similar induction of AR in human blood lymphocytes that had been pre-exposed to RF (AD) and subsequently treated with a chemical mutagen, mitomycin C (CD). Since XR and mitomycin-C induce different kinds of lesions in cellular DNA, further studies are required to understand the mechanism(s) involved in the RF-induced adaptive response.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.