Evidence map›Paper›PMID 23978384›Full record

ReviewNeuropharmacology2014

The effects of acute alcohol administration on the human brain: insights from neuroimaging.

James M Bjork, Jodi M Gilman

Abstract readReview
In one paragraph

Review in Neuropharmacology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Activation by Alcohol of Prefrontal Layer 5 Pyramidal Neurons Depends on Ascending Dopaminergic Input.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. The Dopamine System in Mediating Alcohol Effects in Humans.Current topics in behavioral neurosciences · 2025
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. A social contextual review of the effects of alcohol on emotion.Pharmacology, biochemistry, and behavior · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

James M BjorkDivision of Clinical Neuroscience and Behavioral Research, National Institute on Drug Abuse, National Institutes of Health, 6001 Executive Blvd, Room 3163, Bethesda, MD 20892, USA. Electronic address: jbjork@mail.nih.gov.
Jodi M GilmanLaboratory of Neuroimaging and Genetics, MGH Division of Psychiatric Neuroscience, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, USA.

Funding

Neurobehavioral Characterization of Social Influence in Drug AddictionK01DA034093 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI GILMAN, JODI · 2013 to 2017
$925k
Intramural NIH HHSNIDA NIH HHS K01 DA034093
6 · The paper itself

Abstract

Over the last quarter century, researchers have peered into the living human brain to develop and refine mechanistic accounts of alcohol-induced behavior, as well as neurobiological mechanisms for development and maintenance of addiction. These in vivo neuroimaging studies generally show that acute alcohol administration affects brain structures implicated in motivation and behavior control, and that chronic intoxication is correlated with structural and functional abnormalities in these same structures, where some elements of these decrements normalize with extended sobriety. In this review, we will summarize recent findings about acute human brain responses to alcohol using neuroimaging techniques, and how they might explain behavioral effects of alcohol intoxication. We then briefly address how chronic alcohol intoxication (as inferred from cross-sectional differences between various drinking populations and controls) may yield individual brain differences between drinking subjects that may confound interpretation of acute alcohol administration effects. This article is part of the Special Issue Section entitled 'Neuroimaging in Neuropharmacology'.

Indexed as

Alcohol-Related DisordersBrainCentral Nervous System DepressantsCerebrovascular CirculationCognition DisordersEthanolHumansNeuroimagingRadionuclide ImagingCentral Nervous System DepressantsEthanolAddictionAlcoholfMRINeuroimagingPositron Emission Tomography

Identifiers

PMID23978384
PMCPMC3971012

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.