Evidence map›Paper›PMID 23978003›Full record

ReviewExpert review of respiratory medicine2013

Mitochondria in lung diseases.

Bharathi Aravamudan, Michael A Thompson, Christina M Pabelick, Y S Prakash

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of respiratory medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Nicotine affects mitochondrial structure and function in human airway smooth muscle cells.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  6. Sex-specific lung inflammation and mitochondrial damage in a model of electronic cigarette exposure in asthma.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Mitochondria signaling pathways in allergic asthma.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2022
    Review
  12. Review
  13. Article
  14. Stereology as the 3D tool to quantitate lung architecture.Histochemistry and cell biology · 2021
    Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bharathi AravamudanDepartments of Anesthesiology, Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55905 USA.
Michael A Thompson
Christina M Pabelick
Y S Prakash
Mayo Clinic · USMayo Clinic in Florida · US

Funding

NEURAL REGULATION OF AIRWAYS DURING POSTNATAL MATURATIONR01HL056470 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 1996 to 2025
$10.5M
Neurotrophins in the LungR01HL088029 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 2009 to 2022
$5.9M
The Role of Caveolins in Lung InflammationR01HL090595 · NHLBI · MAYO CLINIC ROCHESTER · PI PABELICK, CHRISTINA MARIA · 2009 to 2013
$1.9M
NHLBI NIH HHS HL056470NHLBI NIH HHS HL090595NHLBI NIH HHS R01 HL056470NHLBI NIH HHS R01 HL088029NHLBI NIH HHS R01 HL090595
6 · The paper itself

Abstract

Mitochondria are autonomous cellular organelles that oversee a variety of functions such as metabolism, energy production, calcium buffering and cell fate determination. Regulation of their morphology and diverse activities beyond energy production are being recognized as playing major roles in cellular health and dysfunction. This review is aimed at summarizing what is known regarding mitochondrial contributions to pathogenesis of lung diseases. Emphasis is given to understanding the importance of structural and functional aspects of mitochondria in both normal cellular function (based on knowledge from other cell types) and in development and modulation of lung diseases such as asthma, chronic obstructive pulmonary disease, cystic fibrosis and cancer. Emerging techniques that allow examination of mitochondria, and potential strategies to target mitochondria in the treatment of lung diseases are also discussed.

Indexed as

HumansLung DiseasesMembrane Potential, MitochondrialMitochondriaMitochondrial Dynamics

Identifiers

PMID23978003
PMCPMC3977638
OpenAlexW2084818692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.