ArticleAnnals of cardiothoracic surgery2013
Systematic review and meta-analysis of transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis.
Article in Annals of cardiothoracic surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 4 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- Evaluating long-term outcomes and the impact of small aortic annulus on valve replacement-a novel systematic review and meta-analysis comparing surgery vs. transcatheter interventions.Frontiers in cardiovascular medicine · 2025Pooled it
- Comparison of transcatheter aortic valve implantation with other approaches to treat aortic valve stenosis: a systematic review and meta-analysis.Systematic reviews · 2019Pooled it
- Pooled it
- Functional status and quality of life after transcatheter aortic valve replacement: a systematic review.Annals of internal medicine · 2014Pooled it
- A Narrative Review of the Evidence for Transcatheter Aortic Valve Implants.Journal of cardiovascular development and disease · 2025Review
- One-year Outcomes of Permanent Pacemaker Implantation after Transcatheter Aortic Valve Replacement: CONDUCT Registry: A Propensity Score-Matched Comparison.Arrhythmia & electrophysiology review · 2025Article
- Pre-TAVI imaging: an Italian survey by the CT PRotocol optimization (CT-PRO) group.The international journal of cardiovascular imaging · 2024Article
- Observational
- Prediction of permanent pacemaker implantation after transcatheter aortic valve replacement: The role of machine learning.World journal of cardiology · 2023Article
- Long-term survival after Carpentier-Edwards Perimount aortic valve replacement in Western Denmark: a multi-centre observational study.Journal of cardiothoracic surgery · 2021Observational
- Recovery of conduction disorders after sutureless aortic valve replacement.Interactive cardiovascular and thoracic surgery · 2021Article
- Three-dimensional printing for cardiovascular diseases: from anatomical modeling to dynamic functionality.Biomedical engineering online · 2020Review
- A systematic review and meta-analysis of the clinical outcomes of TAVI versus SAVR in the octogenarian population.Indian journal of thoracic and cardiovascular surgery · 2020Article
- Long-term outcomes of sutureless and rapid-deployment aortic valve replacement: a systematic review and meta-analysis.Annals of cardiothoracic surgery · 2020Article
- A validated computational framework to predict outcomes in TAVI.Scientific reports · 2020Article
- New Insights into Valve Hemodynamics.Rambam Maimonides medical journal · 2020Review
- Perioperative Stroke.Current neurology and neuroscience reports · 2020Review
- In Vitro Durability and Stability Testing of a Novel Polymeric Transcatheter Aortic Valve.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2020Article
- Principles of TAVR valve design, modelling, and testing.Expert review of medical devices · 2018Review
- Realistic Vascular Replicator for TAVR Procedures.Cardiovascular engineering and technology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscatheter aortic valve implantation (TAVI) has emerged as an acceptable treatment modality for patients with severe aortic stenosis who are deemed inoperable by conventional surgical aortic valve replacement (AVR). However, the role of TAVI in patients who are potential surgical candidates remains controversial.
methodsA systematic review was conducted using five electronic databases, identifying all relevant studies with comparative data on TAVI versus AVR. The primary endpoint was all-cause mortality. A number of periprocedural outcomes were also assessed according to the Valve Academic Research Consortium endpoint definitions.
resultsFourteen studies were quantitatively assessed and included for meta-analysis, including two randomized controlled trials and eleven observational studies. Results indicated no significant differences between TAVI and AVR in terms of all-cause and cardiovascular related mortality, stroke, myocardial infarction or acute renal failure. A subgroup analysis of randomized controlled trials identified a higher combined incidence of stroke or transient ischemic attacks in the TAVI group compared to the AVR group. TAVI was also found to be associated with a significantly higher incidence of vascular complications, permanent pacemaker requirement and moderate or severe aortic regurgitation. However, patients who underwent AVR were more likely to experience major bleeding. Both treatment modalities appeared to effectively reduce the transvalvular mean pressure gradient.
conclusionsThe available data on TAVI versus AVR for patients at a higher surgical risk showed that major adverse outcomes such as mortality and stroke appeared to be similar between the two treatment modalities. Evidence on the outcomes of TAVI compared with AVR in the current literature is limited by inconsistent patient selection criteria, heterogeneous definitions of clinical endpoints and relatively short follow-up periods. The indications for TAVI should therefore be limited to inoperable surgical candidates until long-term data become available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.