Evidence map›Paper›PMID 23976901›Full record

ArticleCellular and molecular bioengineering2011

An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes).

Sheldon Weinbaum, Yi Duan, Mia M Thi, Lidan You

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular bioengineering, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Mechanostat parameters estimated from time-lapsedFrontiers in bioengineering and biotechnology · 2023
    Article
  6. Article
  7. Article
  8. Plastin 3 in health and disease: a matter of balance.Cellular and molecular life sciences : CMLS · 2021
    Review
  9. Article
  10. The Rheology of the Carotid Sinus: A Path Toward Bioinspired Intervention.Frontiers in bioengineering and biotechnology · 2021
    Review
  11. Organ-Specific Branching Morphogenesis.Frontiers in cell and developmental biology · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Microfluidics for the study of mechanotransduction.Journal of physics D: Applied physics · 2020
    Article
  16. Review
  17. Mechano-Regulation of Trabecular Bone Adaptation Is Controlled by the LocalFrontiers in bioengineering and biotechnology · 2020
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Sheldon WeinbaumDepartment of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA.
Yi Duan
Mia M Thi
Lidan You
City College of New York · USKCI (United States) · USUniversity of Toronto · CAYeshiva University · US

Funding

NEW APPROACH TO ENDOTHELIAL CLEFT STRUCTURER01HL044485 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI CURRY, FITZ-ROY E · 1991 to 2010
$4.0M
Axial Flow Effects in Proximal TubuleR01DK062289 · NIDDK · YALE UNIVERSITY · PI WANG, TONG WANG · 2003 to 2012
$2.9M
Structural, Molecular, and Functional Specialization in Osteocyte MechanosensingR01AR057139 · NIAMS · CITY COLLEGE OF NEW YORK · PI SCHAFFLER, MITCHELL B, SPRAY, DAVID C · 2010 to 2014
$2.5M
Cytoskeletal Strain Amplification due to Bone Fluid FlowR01AR048699 · NIAMS · CITY COLLEGE OF NEW YORK · PI WEINBAUM, SHELDON · 2002 to 2006
$1.7M
Defective flow-dependent tubule transport in the pathogenesis of kidney diseaseR01DK117650 · NIDDK · YALE UNIVERSITY · PI WANG, TONG WANG · 2019 to 2022
$1.5M
NHLBI NIH HHS R01 HL044485NIAMS NIH HHS R01 AR048699NIAMS NIH HHS R01 AR057139NIDDK NIH HHS R01 DK062289NIDDK NIH HHS R01 DK117650
6 · The paper itself

Abstract

In this review we will examine from a biomechanical and ultrastructural viewpoint how the cytoskeletal specialization of three basic cell types, endothelial cells (ECs), epithelial cells (renal tubule) and dendritic cells (osteocytes), enables the mechano-sensing of fluid flow in both their native

Indexed as

Actin cortical webActin filament bundlesBone cell processesBrush border microvilliCortical collecting ductEndothelial glycocalyxIntegrin attachmentsLacunar-canalicular systemProximal tubule

Identifiers

PMID23976901
PMCPMC3748935
OpenAlexW2009618390

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.