Evidence map›Paper›PMID 23976803›Full record

ArticleActa astronautica2013

Prediction of trabecular bone qualitative properties using scanning quantitative ultrasound.

Yi-Xian Qin, Wei Lin, Erik Mittra, Yi Xia, Jiqi Cheng, Stefan Judex, Clint Rubin, Ralph Müller

Open access · greenAbstract read
In one paragraph

Article in Acta astronautica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Ultrasonic Assessment of Cancellous Bone Based on the Two-Wave Phenomenon.Advances in experimental medicine and biology · 2022
    Article
  4. Article
  5. Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2020
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Yi-Xian QinStony Brook University, Department of Biomedical Engineering, Bioengineering Building, Rm 215, Stony Brook, NY 11794-5281, United States.
Wei Lin
Erik Mittra
Yi Xia
Jiqi Cheng
Stefan Judex
Clint Rubin
Ralph Müller
Stony Brook University · USETH Zurich · CH

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
Functional Fluid Flow Regulated Bone RegenerationR01AR061821 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2012 to 2016
$1.7M
Role of Musculo-Dynamics in Bone Fluid Flow, Circulation and AdaptationR01AR052379 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2005 to 2009
$1.7M
Bone Fluid Flow and its Regulatory Role in AdaptationR01AR049286 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2003 to 2006
$1.1M
NIAMS NIH HHS R01 AR049286NIAMS NIH HHS R01 AR052379NIAMS NIH HHS R01 AR061821NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

Microgravity induced bone loss represents a critical health problem in astronauts, particularly occurred in weight-supporting skeleton, which leads to osteopenia and increase of fracture risk. Lack of suitable evaluation modality makes it difficult for monitoring skeletal status in long term space mission and increases potential risk of complication. Such disuse osteopenia and osteoporosis compromise trabecular bone density, and architectural and mechanical properties. While X-ray based imaging would not be practical in space, quantitative ultrasound may provide advantages to characterize bone density and strength through wave propagation in complex trabecular structure. This study used a scanning confocal acoustic diagnostic and navigation system (SCAN) to evaluate trabecular bone quality in 60 cubic trabecular samples harvested from adult sheep. Ultrasound image based SCAN measurements in structural and strength properties were validated by μCT and compressive mechanical testing. This result indicated a moderately strong negative correlations observed between broadband ultrasonic attenuation (BUA) and μCT-determined bone volume fraction (BV/TV, R

Indexed as

bone adaptationbone loss in spacebone mineral densitybone qualitydisuse osteoporosisdual-energy X-ray absorptiometryquantitative ultrasoundscanning confocal ultrasoundspeed of soundultrasound attenuationultrasound velocity

Identifiers

PMID23976803
PMCPMC3747567
OpenAlexW2070557756

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.