ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2014
Fatigue interference with daily living among patients with inflammatory bowel disease.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Interventions for fatigue in inflammatory bowel disease.The Cochrane database of systematic reviews · 2020Pooled it
- A Treat-to-Target Update in Ulcerative Colitis: A Systematic Review.The American journal of gastroenterology · 2019Pooled it
- Fatigue as an Extra-Intestinal Manifestation of Celiac Disease: A Systematic Review.Nutrients · 2018Pooled it
- Trial
- Fatigue in inflammatory bowel disease: Prevalence, risk factors, assessment, outcomes, and management.World journal of gastrointestinal pathophysiology · 2025Review
- Multidimensional fatigue mediates the relationship between sexual quality of life and perceived stress in patients with inflammatory bowel disease.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025Article
- The Substantial Role of Sleep, Stress, and Physical Activity in Persistent High Levels of Fatigue in Patients With Inflammatory Bowel Disease: A Longitudinal Trajectory Study.Journal of Crohn's & colitis · 2025Article
- Sexual Health in Women with Inflammatory Bowel Diseases: A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- Impact of Nursing Interventions via Telephone and Email on the Quality of Life of Patients with Inflammatory Bowel Disease: Preliminary Results of a Comparative Observational Study.Healthcare (Basel, Switzerland) · 2024Article
- Unraveling the fatigue puzzle: insights into the pathogenesis and management of IBD-related fatigue including the role of the gut-brain axis.Frontiers in medicine · 2024Review
- Psychometric properties of the 12-item Stroke-Specific Quality of Life Scale among stroke survivors in Hong Kong.Scientific reports · 2023Article
- Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study.BMC gastroenterology · 2022Article
- Systematic review: the impact of inflammatory bowel disease-related fatigue on health-related quality of life.Frontline gastroenterology · 2021Article
- Toward Further Understanding of Crohn's Disease-Related Fatigue: The Role of Depression and Emotional Processing.Frontiers in psychology · 2020Article
- The relationship between the symptom of fatigue and the functioning of patients with inflammatory bowel diseases after surgery.Przeglad gastroenterologiczny · 2019Article
- Unmet Needs in IBD: the Case of Fatigue.Clinical reviews in allergy & immunology · 2018Review
- Psychological distress, iron deficiency, active disease and female gender are independent risk factors for fatigue in patients with ulcerative colitis.United European gastroenterology journal · 2018Article
- Pain may be an important factor to consider in inflammatory bowel disease patients troubled by fatigue.United European gastroenterology journal · 2017Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of the study was to examine fatigue interference with daily living in patients with inflammatory bowel disease (IBD) and to explore relationships between severe fatigue interference and socio-demographic and clinical variables, including use of complementary and alternative medicine (CAM).
methodsData were collected using self-report questionnaires from adult IBD outpatients. Fatigue interference was assessed with the 5-item Fatigue Severity Scale, and scores ≥ 5 were defined as severe fatigue interference. CAM use was assessed with the International CAM Questionnaire. Multivariate logistic regression analysis was used to examine associations between severe fatigue interference and socio-demographic factors, clinical factors, and CAM use.
resultsIn total, 428 patients had evaluable questionnaires (response rate 93 %). Severe fatigue interference was reported by 39 % of the total sample. Patients with Crohn's disease (CD) (n = 238) were more likely than patients with ulcerative colitis (UC) (n = 190) to report severe fatigue interference (43 and 33 %, respectively, p = 0.003). In addition, patients reporting severe fatigue interference were more likely to have active disease than patients without severe fatigue interference (p < 0.001 for both diagnoses). Patients with inactive disease had scores comparable to the general population. Factors independently associated with severe fatigue interference in UC included disease activity and CAM use, while in CD they included disease activity and current smoking.
conclusionsSevere fatigue interference is common among IBD patients with active disease. Among patients with UC, but not CD, CAM use was associated with severe fatigue interference. The relationship between fatigue interference and personal factors should be considered further in subsequent studies.
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