Evidence map›Paper›PMID 23975276›Full record

ArticleBrain imaging and behavior2014

The perfect neuroimaging-genetics-computation storm: collision of petabytes of data, millions of hardware devices and thousands of software tools.

Ivo D Dinov, Petros Petrosyan, Zhizhong Liu, Paul Eggert, Alen Zamanyan, Federica Torri, Fabio Macciardi, Sam Hobel, Seok Woo Moon, Young Hee Sung and 9 more

Abstract read
In one paragraph

Article in Brain imaging and behavior, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Volume and Value of Big Healthcare Data.Journal of medical statistics and informatics
    Article
  10. Article
  11. Sharing big biomedical data.Journal of big data
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ivo D DinovLaboratory of Neuro Imaging (LONI), David Geffen School of Medicine at UCLA, University of California, Los Angeles, 635 S. Charles Young Drive, Suite 225, Los Angeles, CA, 90095-7334, USA, dinov@ucla.edu.
Petros Petrosyan
Zhizhong Liu
Paul Eggert
Alen Zamanyan
Federica Torri
Fabio Macciardi
Sam Hobel
Seok Woo Moon
Young Hee Sung
Zhiguo Jiang
Jennifer Labus
Florian Kurth
Cody Ashe-McNalley
Emeran Mayer
Paul M Vespa
John D Van Horn
Arthur W Toga
Alzheimer’s Disease Neuroimaging Initiative

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
UCLA ALZHEIMERS DISEASE RESEARCH CENTERP50AG016570 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CUMMINGS, JEFFREY L. · 1999 to 2014
$25.9M
FUNCTION BIRNU24RR021992 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI POTKIN, STEVEN G · 2006 to 2010
$25.0M
BIO-INFORMATICS RESEARCH NETWORK COORDINATING CENTER (BIRN-CC)U24RR025736 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KESSELMAN, CARL · 2009 to 2011
$15.0M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2012 to 2022
$14.1M
Bio-Informatics Research Network Coordinating Center (BIRN-CC)U24GM104203 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KESSELMAN, CARL · 2012 to 2013
$8.3M
Collaborative Brain Mapping: Tools for SharingR01MH071940 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TOGA, ARTHUR W · 2004 to 2008
$3.2M
Computional Brain Biology from Genotype to PhenotypeP20MH065166 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TOGA, ARTHUR W · 2002 to 2004
$3.1M
DIGITAL REPRESENTATION AND VISUALIZATION OF HUMAN BRAINR01LM005639 · NLM · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI TOGA, ARTHUR W · 1995 to 2005
$1.8M
NCRR NIH HHS U24 RR021992NCRR NIH HHS U24-RR021992NCRR NIH HHS U24 RR025736NCRR NIH HHS U24-RR025736NIA NIH HHS P 50 AG16570NIA NIH HHS U01 AG024904NIBIB NIH HHS P41 EB015922NIBIB NIH HHS P41EB015922NIGMS NIH HHS U24 GM104203NIMH NIH HHS P20 MH065166NIMH NIH HHS R01 MH071940NLM NIH HHS LM05639NLM NIH HHS R01 LM005639
6 · The paper itself

Abstract

The volume, diversity and velocity of biomedical data are exponentially increasing providing petabytes of new neuroimaging and genetics data every year. At the same time, tens-of-thousands of computational algorithms are developed and reported in the literature along with thousands of software tools and services. Users demand intuitive, quick and platform-agnostic access to data, software tools, and infrastructure from millions of hardware devices. This explosion of information, scientific techniques, computational models, and technological advances leads to enormous challenges in data analysis, evidence-based biomedical inference and reproducibility of findings. The Pipeline workflow environment provides a crowd-based distributed solution for consistent management of these heterogeneous resources. The Pipeline allows multiple (local) clients and (remote) servers to connect, exchange protocols, control the execution, monitor the states of different tools or hardware, and share complete protocols as portable XML workflows. In this paper, we demonstrate several advanced computational neuroimaging and genetics case-studies, and end-to-end pipeline solutions. These are implemented as graphical workflow protocols in the context of analyzing imaging (sMRI, fMRI, DTI), phenotypic (demographic, clinical), and genetic (SNP) data.

Indexed as

AlgorithmsInternetSoftwareWorkflowAlzheimer DiseaseBrainBrain InjuriesChronic PainComputational BiologyFemaleGenome-Wide Association StudyGenomicsHumansInformation DisseminationIrritable Bowel SyndromeMale

Identifiers

PMID23975276
PMCPMC3933453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.