ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
Oral status of patients submitted to autologous hematopoietic stem cell transplantation.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Systemic implications of endodontic and periodontal infections in hematopoietic stem cell transplantation: a systematic review.Clinical oral investigations · 2025Pooled it
- Bismuth adjuvant ameliorates adverse effects of high-dose chemotherapy in patients with multiple myeloma and malignant lymphoma undergoing autologous stem cell transplantation: a randomised, double-blind, prospective pilot study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Trial
- Oral Hygiene Management of Hematologic Patients Undergoing Auto-Transplantation: An Observational Study.Dentistry journal · 2025Article
- Influence of periodontal status on patients undergoing hematopoietic stem cell transplantation: A retrospective analysis.Heliyon · 2024Article
- Dental evaluation and clearance prior to allogeneic hematopoietic cell transplantation.Oral diseases · 2024Article
- Oral microbial changes, oral mucositis and febrile neutropenia during myelosuppressive chemotherapy in patients diagnosed with a solid tumor or lymphoma.Frontiers in oral health · 2024Article
- Impact of periodontal status on the oral mucositis in patients receiving high-dose chemotherapy.Clinical oral investigations · 2022Article
- A retrospective study comparing oral health in cancer patients and healthy people.European journal of translational myology · 2022Article
- Dental status and risk of odontogenic complication in patients undergoing hematopoietic stem cell transplant.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Oral disorders in patients with newly diagnosed haematological diseases.Clinical oral investigations · 2020Article
- Dental treatment needs in hospitalized cancer patients: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Local analgesic effect of a bioadhesive barrier-forming oral liquid in cancer patients with oral mucositis caused by chemotherapy and/or radiotherapy: a randomized multicenter, single-use, positive-controlled, open-label study.OncoTargets and therapy · 2018Article
- Cambra system in patients awaiting hematopoietic progenitor cell transplant and high caries risk.Journal of clinical and experimental dentistry · 2017Article
- Mucositis and oral infections secondary to gram negative rods in patients with prolonged neutropenia.IDCases · 2017Article
- Self-reported oral health and quality of life of postmenopausal breast cancer survivors on aromatase inhibitors and women without cancer diagnoses: a longitudinal analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- Effects of Hangeshashinto on Growth of Oral Microorganisms.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Appropriate and necessary oral care for people with cancer: guidance to obtain the right oral and dental care at the right time.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014Review
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOral infection may be a source of bacteremia in patients undergoing hematopoietic stem cell transplant (HSCT). The aim of this study was to evaluate the relationship between patients with poor periodontal status and complications after HSCT.
methodsA cohort of patients with hematological malignancies candidates for autologous HSCT was observed before and during the neutropenic phase of HSCT. A primary evaluation was performed before the HSCT procedure, including medical and socio-demographic data and physical examination (number of teeth and decayed, missing and filled teeth index (DMFT), oral mucosa, and full mouth periodontal assessment). During the neutropenic phase, data regarding the development of febrile neutropenia, bacteremia, and mucositis were also prospectively obtained.
resultsForty-eight patients were included. The most common baseline disease was multiple myeloma (70 %). In the primary evaluations, the median DMFT was 13 (ranging 0-27), and periodontitis and gingivitis were present in 29 and 60 % of the patients, respectively. During the neutropenic phase of HSCT, fever occurred in 96 % of patients, and bacteremia was documented in 29 %. Coagulase-negative Staphylococcus was the most common isolated bacteria. Patients who developed bacteremia had a higher frequency of oral disorders compared with those without bacteremia, but it was not statistically significant. Oral mucositis affected 89.6 % of the patients, and patients with gingivitis or periodontal disorders had a high frequency of mucositis.
conclusionsThe prevalence of oral pathologic conditions previous to HSCT procedures was very high in the studied population. A possible association was noted between previous gingivitis and the development of mucositis during the neutropenia of HSCT.
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