Evidence map›Paper›PMID 23974704›Full record

ReviewScience China. Life sciences2013

MicroRNAs in cardiac regeneration and cardiovascular disease.

Gengze Wu, Zhan-Peng Huang, Da-Zhi Wang

Abstract readReview
In one paragraph

Review in Science China. Life sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Non-coding RNAs in Cardiac Regeneration.Frontiers in physiology · 2021
    Review
  8. Article
  9. Review
  10. How cardiomyocytes sense pathophysiological stresses for cardiac remodeling.Cellular and molecular life sciences : CMLS · 2017
    Review
  11. Article
  12. Article
  13. MicroRNA delivery for regenerative medicine.Advanced drug delivery reviews · 2015
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gengze WuDepartment of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.
Zhan-Peng Huang
Da-Zhi Wang

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
MicroRNAs, cardiac development and functionR01HL085635 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WANG, DA-ZHI · 2007 to 2015
$3.2M
Molecular Mechanisms of Dilated CardiomyopathyR01HL116919 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI WANG, DA-ZHI · 2013 to 2016
$1.7M
NHLBI NIH HHS HL085635NHLBI NIH HHS R01 HL085635NHLBI NIH HHS R01 HL116919NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

microRNAs (miRNAs) are a class of small non-coding RNAs, which have been shown important to a wide range of biological process by post-transcriptionally regulating the expression of protein-coding genes. miRNAs have been demonstrated essential to normal cardiac development and function. Recently, numerous studies indicate miRNAs are involved in cardiac regeneration and cardiac disease, including cardiac hypertrophy, myocardial infarction and cardiac arrhythmia. These observations suggest miRNAs play important roles in cardiology. In this review, we summarize the recent progress of studying miRNAs in cardiac regeneration and cardiac disease. We also discuss the diagnostic and therapeutic potential of miRNAs in heart disease.

Indexed as

AnimalsGene Expression RegulationHeartHeart DiseasesHumansMicroRNAsMyocardiumRegenerationMicroRNAs

Identifiers

PMID23974704
PMCPMC3972258

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.