Evidence map›Paper›PMID 23974286›Full record

ReviewCurrent genetics2013

Lipids of Candida albicans and their role in multidrug resistance.

Rajendra Prasad, Ashutosh Singh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 44 citations in OpenAlex.

  1. Identification of efflux inhibitors through a drug repurposing strategy inFrontiers in cellular and infection microbiology · 2026
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  5. Unmasking the Antifungal Activity ofJournal of fungi (Basel, Switzerland) · 2024
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  16. Frontiers in microbiology · 2018
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rajendra PrasadMembrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 110067, India, rp47@mail.jnu.ac.in.
Ashutosh Singh
Jawaharlal Nehru University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years, lipids of non-pathogenic yeast such as Saccharomyces cerevisiae have been characterized to some details; however, a comparable situation does not exist for the human pathogenic fungi. This review is an attempt to bring in recent advances made in lipid research by employing high throughput lipidomic methods in terms of lipid analysis of pathogenic yeasts. Several pathogenic fungi exhibit multidrug resistance (MDR) which they acquire during the course of a treatment. Among the several causal factors, lipids by far have emerged as one of the critical contributors in the MDR acquisition in human pathogenic Candida. In this article, we have particularly focused on the role of lipids involved in cross talks between different cellular circuits that impact the acquisition of MDR in Candida.

Indexed as

Models, MolecularATP-Binding Cassette TransportersAzolesCandida albicansDrug Resistance, MultipleErgosterolHigh-Throughput Screening AssaysLipidsMolecular StructureProtein ConformationReceptor Cross-TalkSphingolipidsATP-Binding Cassette TransportersAzolesErgosterolLipidsSphingolipids

Identifiers

PMID23974286
OpenAlexW2089939893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.